Evidence map›Paper›PMID 24936089›Full record

ReviewSchizophrenia bulletin2014

From tones in tinnitus to sensed social interaction in schizophrenia: how understanding cortical organization can inform the study of hallucinations and psychosis.

Dominic H Ffytche, Cynthia G Wible

Open access · bronzeAbstract readReview
In one paragraph

Review in Schizophrenia bulletin, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

  1. Trial
  2. Article
  3. How dopamine guides our social world.Pharmacological reviews · 2025
    Review
  4. Psychotic Symptoms in Patients With Major Neurological Diseases.Journal of clinical neurology (Seoul, Korea) · 2024
    Review
  5. Article
  6. Article
  7. Review
  8. NeuroImage. Clinical · 2019
    Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Dominic H FfytcheDepartment of Old Age Psychiatry, Institute of Psychiatry, King's College London, De Crespigny Park, London, UK;
Cynthia G WibleHarvard Medical School, VA Boston Healthcare System, Brockton, MA cindy@bwh.harvard.edu.
Harvard University · USKing's College London · GB

Funding

NEUROPHYSIOLOGICAL STUDIES OF SCHIZOPHRENIAR01MH040799 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI MCCARLEY, ROBERT W · 1986 to 2011
$6.5M
BIOLOGICAL BASIS OF SCHIZOTYPAL PERSONALITY DISORDERR01MH052807 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI MCCARLEY, ROBERT W · 1994 to 2009
$3.3M
Auditory-verbal functional studies of schizophreniaR01MH067080 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WIBLE, CYNTHIA G · 2005 to 2009
$1.4M
Department of Health RP-PG-0610-10100NIMH NIH HHS 1R01 MH067080-01A2NIMH NIH HHS 1R01 MH52807NIMH NIH HHS MH40799
6 · The paper itself

Abstract

The content, modality, and perceptual attributes of hallucinations and other psychotic symptoms may be related to neural representation at a single cell and population level in the cerebral cortex. A brief survey of some principles and examples of cortical representation and organization will be presented together with evidence for a correspondence between the neurobiology of brain areas activated at the time of a hallucination and the content of the corresponding hallucinatory and psychotic experiences. Contrasting the hallucinations of schizophrenia with other conditions, we highlight phenomenological aspects of hallucinations that are ignored in clinical practice but carry potentially important information about the brain regions and dysfunctions underlying them. Knowledge of cortical representation and organization are being used to develop animal models of hallucination and to test treatments that are now beginning to translate to the clinical domain.

Indexed as

Interpersonal RelationsBrain MappingCerebral CortexHallucinationsHumansNeural PathwaysPsychotic DisordersSchizophreniaTinnituscortexhallucinationheteromodaljunctionmultimodalitynetworktemporal parietalunimodal

Identifiers

PMID24936089
PMCPMC4141315
OpenAlexW2114929101

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.