ArticleJournal of dental research2014
Association of Carotid Intima-media Thickness and Atherosclerotic Plaque with Periodontal Status.
Article in Journal of dental research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Association between atherosclerosis and tooth loss in adult patients: systematic review and meta-analysis.Evidence-based dentistry · 2026Pooled it
- Periodontitis, subclinical myocardial injury, and cardiovascular mortality among US adults: a population-based study.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025Article
- [Periodontitis and systemic diseases: Thinking and explorations].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2025Review
- Oral Disease and Atherosclerosis May Be Associated with Overlapping Metabolic Pathways.JDR clinical and translational research · 2025Article
- Usefulness of the CDC/AAP and the EFP/AAP Criteria to Detect Subclinical Atherosclerosis in Subjects with Diabetes and Severe Periodontal Disease.Diagnostics (Basel, Switzerland) · 2025Article
- Relationship between Carotid Intima-Media Thickness, Periodontal Disease, and Systemic Inflammation Biomarkers in an Adult Population.Biomedicines · 2024Article
- Functional mutation, splice, distribution, and divergence analysis of impactful genes associated with heart failure and other cardiovascular diseases.Scientific reports · 2023Article
- Effect of endodontic treatment on endothelial dysfunction and subclinical atherosclerosis-a prospective intervention study.Clinical oral investigations · 2023Article
- Association of severely damaged endodontically infected tooth with carotid plaque and abnormal carotid intima-media thickness: a retrospective analysis.Clinical oral investigations · 2023Article
- Periodontitis and implant complications in diabetes.Periodontology 2000 · 2022Review
- Regular dental visits, periodontitis, tooth loss, and atherosclerosis: The Ohasama study.Journal of periodontal research · 2022Article
- An updated review on the link between oral infections and atherosclerotic cardiovascular disease with focus on phenomics.Frontiers in physiology · 2022Review
- Association of Edentulism with Various Chronic Diseases in Mexican Elders 60+ Years: Results of a Population-Based Survey.Healthcare (Basel, Switzerland) · 2021Article
- Association between Periodontal Disease and Comorbidities in Saudi's Eastern Province.BioMed research international · 2021Article
- [Effect ofBeijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2020Article
- Assessment of Periodontal Status Based on Carotid Artery Intima Media Thickness.Oral health & preventive dentistry · 2020Article
- Periodontal diseases and carotid intima-media thickness in Bangladesh.Journal of clinical periodontology · 2016Article
- The association of active and secondhand smoking with oral health in adults: Japan public health center-based study.Tobacco induced diseases · 2015Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies have suggested an association between clinical/subclinical atherosclerosis and periodontal status. The purpose of this study was to investigate the association among maximal carotid intima-media thickness (cIMT), atherosclerotic plaque, and periodontal status in Chinese elderly patients. A cross-sectional study was conducted of 847 participants (age, 70.64 ± 9.03 yr) with ≥10 teeth. A questionnaire survey, routine biochemical tests, a periodontal examination, and maximal cIMT measurement were performed for each. Traditional risk factors for atherogenesis were considered in the statistical analysis. Mean plaque index, which reflects oral hygiene, was correlated with maximal cIMT and atherosclerotic plaque in the study sample overall (β = 0.068, p < .001; OR = 2.051, p < .001) and in euglycemic participants (β = 0.066, p = .008; odds ratio = 2.122, p = .009). In hyperglycemic participants, multiple linear regression analysis (p = .006) and multivariate logistic regression analysis (p = .025) revealed a linear and dose-dependent association between mean clinical attachment loss and maximal cIMT after adjustment for traditional risk factors. Each 1-mm increase in mean clinical attachment loss corresponded to a 0.018-mm increase in maximal cIMT. The risk of atherosclerotic plaque increased by 18.3% with each 1-mm increase in mean clinical attachment loss. Other indicators of periodontal exposure, including percentage of sites with attachment loss ≥ 3 to 5 mm (3%-5%), were also correlated with cIMT and atherosclerotic plaque in hyperglycemic patients. In this elderly population, a linear and dose-dependent association among mean clinical attachment loss, attachment loss 3% to 5%, maximal cIMT, and atherosclerotic plaque was verified in those with hyperglycemia. Poor oral hygiene was correlated with maximal cIMT and atherosclerotic plaque in all participants, including those with normal blood glucose.
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