ArticleThe Plant cell2014
Subcellular Relocalization and Positive Selection Play Key Roles in the Retention of Duplicate Genes of Populus Class III Peroxidase Family.
Article in The Plant cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
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Who cites it
52 citing papers in PubMed, 108 citations in OpenAlex.
- Uncovering the genome evolutionary dynamics of the Mediterranean endemic palm Chamaerops humilis.BMC plant biology · 2026Article
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- Integrated genomic, transcriptomic, and proteomic analyses prioritize cadmium-responsive class III peroxidases inFrontiers in plant science · 2026Article
- Genome-wide analysis of class III peroxidase gene family in Glycine max and functional roles in stress response.Scientific reports · 2025Article
- AtPrx71-mediated regulation of stem elongation, gravitropic response, and IAA accumulation in Arabidopsis.Planta · 2025Article
- Comparative analysis of POD gene family and expression differentiation under NaCl, HBMC genomics · 2025Article
- An Updated Review on Essential Oils from Lauraceae Plants: Chemical Composition and Genetic Characteristics of Biosynthesis.International journal of molecular sciences · 2025Review
- Functional analysis of CYP4B1 enzymes from apes and humans uncovers evolutionary hot spots for adaptations of the catalytical function.PLoS genetics · 2025Article
- The Class III Peroxidase Gene Family inAntioxidants (Basel, Switzerland) · 2025Article
- Writers, readers, and erasers of N6-Methyladenosine (m6A) methylomes in oilseed rape: identification, molecular evolution, and expression profiling.BMC plant biology · 2025Article
- Enhanced Immune Response Against Echinococcus Granulosus Through a CTLA-4/B7 Affinity-Based Vaccine.Vaccines · 2024Article
- Integration of Genome-Wide Identification and Transcriptome Analysis of Class III Peroxidases inInternational journal of molecular sciences · 2024Article
- Physiology and molecular biology of plants : an international journal of functional plant biology · 2024Article
- RNA-seq-based comparative transcriptome analysis reveals the role ofHorticulture research · 2024Article
- Genome-Wide Investigation of Class III Peroxidase Genes inPlants (Basel, Switzerland) · 2024Article
- Heterologous expression of Arabidopsis laccase2, laccase4 and peroxidase52 driven under developing xylem specific promoter DX15 improves saccharification in populus.Biotechnology for biofuels and bioproducts · 2024Article
- Class III Peroxidases in the Peach (Plants (Basel, Switzerland) · 2024Article
- Comprehensive identification, characterization and expression analyses of the class III POD gene family in water lily (Frontiers in plant science · 2024Article
- Histochemical Detection of Peroxidase and Laccase Activities in Populus Secondary Xylem.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Genetic Channelization Mechanism of Four Chalcone Isomerase Homologous Genes for Synergistic Resistance to Fusarium wilt inInternational journal of molecular sciences · 2023Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gene duplication is the primary source of new genes and novel functions. Over the course of evolution, many duplicate genes lose their function and are eventually removed by deletion. However, some duplicates have persisted and evolved diverse functions. A particular challenge is to understand how this diversity arises and whether positive selection plays a role. In this study, we reconstructed the evolutionary history of the class III peroxidase (PRX) genes from the Populus trichocarpa genome. PRXs are plant-specific enzymes that play important roles in cell wall metabolism and in response to biotic and abiotic stresses. We found that two large tandem-arrayed clusters of PRXs evolved from an ancestral cell wall type PRX to vacuole type, followed by tandem duplications and subsequent functional specification. Substitution models identified seven positively selected sites in the vacuole PRXs. These positively selected sites showed significant effects on the biochemical functions of the enzymes. We also found that positive selection acts more frequently on residues adjacent to, rather than directly at, a critical active site of the enzyme, and on flexible regions rather than on rigid structural elements of the protein. Our study provides new insights into the adaptive molecular evolution of plant enzyme families.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.