Evidence map›Paper›PMID 24932945›Full record

Trial reportDrug and alcohol dependence2014

Hair drug testing results and self-reported drug use among primary care patients with moderate-risk illicit drug use.

Jan Gryczynski, Robert P Schwartz, Shannon Gwin Mitchell, Kevin E O'Grady, Steven J Ondersma

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Drug and alcohol dependence, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 63 citations in OpenAlex.

  1. Trial
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  8. Expanded taxonomies of human memory.Frontiers in cognition · 2024
    Review
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  11. Interpol review of toxicology 2019-2022.Forensic science international. Synergy · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jan GryczynskiFriends Research Institute, Inc., 1040 Park Avenue, Suite 103, Baltimore, MD 21201, USA. Electronic address: jgryczynski@friendsresearch.org.
Robert P SchwartzFriends Research Institute, Inc., 1040 Park Avenue, Suite 103, Baltimore, MD 21201, USA.
Shannon Gwin MitchellFriends Research Institute, Inc., 1040 Park Avenue, Suite 103, Baltimore, MD 21201, USA.
Kevin E O'GradyUniversity of Maryland, College Park, Department of Psychology, College Park, MD 20742, USA.
Steven J OndersmaWayne State University, 42 W Warren Ave, Detroit, MI 48202, USA.
Friends Research Institute · USUniversity of Maryland, College Park · USWayne State University · US

Funding

SBIRT in New MexicoR01DA026003 · NIDA · FRIENDS RESEARCH INSTITUTE, INC. · PI SCHWARTZ, ROBERT P · 2009 to 2013
$2.5M
NIDA NIH HHS R01 DA026003
6 · The paper itself

Abstract

backgroundThis study sought to examine the utility of hair testing as a research measure of drug use among individuals with moderate-risk drug use based on the internationally validated Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST).

methodsThis study is a secondary analysis using baseline data from a randomized trial of brief intervention for drug misuse, in which 360 adults with moderate-risk drug use were recruited from two community clinics in New Mexico, USA. The current study compared self-reported drug use on the ASSIST with laboratory analysis of hair samples using a standard commercially available 5-panel test with assay screening and gas chromatography/mass spectrometry (GC/MS) confirmation. Both self-report and hair testing covered a 3-month period.

resultsOverall concordance between hair testing and self-report was 57.5% (marijuana), 86.5% (cocaine), 85.8% (amphetamines), and 74.3% (opioids). Specificity of hair testing at standard laboratory cut-offs exceeded 90% for all drugs, but sensitivity of hair testing relative to self-report was low, identifying only 52.3% (127/243) of self-disclosed marijuana users, 65.2% (30/46) of cocaine users, 24.2% (8/33) of amphetamine users, and 2.9% (2/68) of opioid users. Among participants who disclosed using marijuana or cocaine in the past 3 months, participants with a negative hair test tended to report lower-frequency use of those drugs (p<.001 for marijuana and cocaine).

conclusionsHair testing can be useful in studies with moderate-risk drug users, but the potential for under-identification of low-frequency use suggests that researchers should consider employing low detection cut-offs and using hair testing in conjunction with self-report.

Indexed as

AdultAmphetaminesAnalgesics, OpioidCannabinoidsCocaineDrug UsersFemaleGas Chromatography-Mass SpectrometryHairHumansIllicit DrugsMaleMiddle AgedPrimary Health CareSelf ReportSubstance Abuse DetectionAmphetaminesAnalgesics, OpioidCannabinoidsCocaineIllicit DrugsBrief interventionHair testingModerate-risk drug usePrimary careSelf-report

Identifiers

PMID24932945
PMCPMC4080811
OpenAlexW2092811653

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.