Evidence map›Paper›PMID 24932902›Full record

ReviewEuropean journal of medical genetics2014

Infantile hydrocephalus: a review of epidemiology, classification and causes.

Hannah M Tully, William B Dobyns

Open access · greenAbstract readReview
In one paragraph

Review in European journal of medical genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 175 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
175citing papers in PubMed, 3 pooled it
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

175 citing papers in PubMed, 3 syntheses or guidelines pooled it, 397 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Ventriculo-peritoneal shunting devices for hydrocephalus.The Cochrane database of systematic reviews · 2020
    Pooled it
  4. Article
  5. Article
  6. Article
  7. Review
  8. Rehabilitation after diagnosis of hydrocephalus in severe acquired brain injury: the unmet need for evidence-based guidelines.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Review
  9. Review
  10. Review
  11. De NovoHuman mutation · 2026
    Article
  12. Article
  13. Review
  14. Postoperative complications of ventriculoperitoneal shunt in children: experience from a middle-income referral hospital in Lima, Peru.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Article
  15. Rate and risk factors for shunt revision in pediatric patients with hydrocephalus during a 17-year study period: a retrospective, population-based study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Article
  16. Elective intraperitoneal procedures do not adversely impact paediatric ventriculoperitoneal shunt survival: 10-year retrospective cohort study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Article
  17. Emerging insights into primary ciliary dyskinesia-associated hydrocephalus: a scoping review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Article
  18. Article
  19. Benign External Hydrocephalus in a Subgroup of Autistic Children Prior to Autism Diagnosis.Autism research : official journal of the International Society for Autism Research · 2025
    Article
  20. Review

115 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Hannah M TullyDepartment of Neurology, University of Washington, Seattle, WA, USA; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA. Electronic address: hmtully@uw.edu.
William B DobynsDepartment of Pediatrics, Division of Genetic Medicine, University of Washington, Seattle, WA, USA; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.
Seattle Children's Hospital · US

Funding

Institute of Translational Health SciencesKL2TR000421 · NCATS · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2012 to 2016
$12.6M
De novo copy number variation and gene discovery in human brain malformationsR01NS058721 · NINDS · UNIVERSITY OF CHICAGO · PI ARGILLI, EMANUELA · 2008 to 2025
$10.9M
The Genetic Basis of Mid-Hindbrain MalformationsR01NS050375 · NINDS · UNIVERSITY OF MINNESOTA · PI DOBYNS, WILLIAM B. · 2005 to 2019
$9.9M
Institute for Translational Health Science (KL2)KL2RR025015 · NCRR · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2007 to 2011
$9.3M
The Role of ARX in Normal and Abnormal Brain DevelopmentR01NS046616 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI GOLDEN, JEFFREY A · 2005 to 2013
$4.1M
Research Training in NeurologyT32NS051171 · NINDS · UNIVERSITY OF WASHINGTON · PI RANSOM, BRUCE ROBERT · 2007 to 2011
$985k
NCATS NIH HHS KL2 TR000421NCATS NIH HHS KL2TR000421NCRR NIH HHS KL2 RR025015NINDS NIH HHS R01 NS046616NINDS NIH HHS R01NS046616NINDS NIH HHS R01 NS050375NINDS NIH HHS R01NS050375NINDS NIH HHS R01 NS058721NINDS NIH HHS R0NS058721NINDS NIH HHS T32 NS051171NINDS NIH HHS T32NS051171
6 · The paper itself

Abstract

Hydrocephalus is a common but complex condition caused by physical or functional obstruction of CSF flow that leads to progressive ventricular dilatation. Though hydrocephalus was recently estimated to affect 1.1 in 1000 infants, there have been few systematic assessments of the causes of hydrocephalus in this age group, which makes it a challenging condition to approach as a scientist or as a clinician. Here, we review contemporary literature on the epidemiology, classification and pathogenesis of infantile hydrocephalus. We describe the major environmental and genetic causes of hydrocephalus, with the goal of providing a framework to assess infants with hydrocephalus and guide future research.

Indexed as

HydrocephalusAnimalsHumansInfantAqueductal stenosisGeneticsHydrocephalusIntraventricular hemorrhageL1CAM

Identifiers

PMID24932902
PMCPMC4334358
OpenAlexW1974421752

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.