Evidence map›Paper›PMID 24932444›Full record

ArticleMuscles, ligaments and tendons journal2014

Sonographic findings during and after Platelet Rich Plasma injections in tendons.

Michele Abate, Sandra Verna, Patrizia Di Gregorio, Vincenzo Salini, Cosima Schiavone

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Muscles, ligaments and tendons journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03504111 (PRINT Trial), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03504111 naunknown statusnot on this mapstarted 2016, after this paper: background citation

PRINT Trial (Platelet Rich Injections vs. Needle Tenotomy): Evaluation of Ultrasound Guided Procedures for the Treatment of Chronic Tendinosis

TypeinterventionalSponsorKaiser PermanenteRan2016 to 2019Enrolled50ConditionsLateral Epicondylitis, Tendinosis, Elbow, Tennis, Elbows TendonitisArmsPercutaneous Needle Tenotomy, PRP
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Platelet-Rich Plasma Diffusion in Achilles Tendon: Relationship with Therapeutic Outcomes.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2019
    Observational
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Michele AbateDepartment of Medicine and Science of Aging, University G. D'Annunzio, Chieti-Pescara, Chieti Scalo, Italy.
Sandra VernaImmunohaematology and Transfusional Medicine Service, "SS. Annunziata" Hospital, Chieti Scalo, Italy.
Patrizia Di GregorioImmunohaematology and Transfusional Medicine Service, "SS. Annunziata" Hospital, Chieti Scalo, Italy.
Vincenzo SaliniDepartment of Medicine and Science of Aging, University G. D'Annunzio, Chieti-Pescara, Chieti Scalo, Italy.
Cosima SchiavoneDepartment of Medicine and Science of Aging, University G. D'Annunzio, Chieti-Pescara, Chieti Scalo, Italy.
University of Chieti-Pescara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Platelet rich plasma has been used in the treatment of tendinopathies, but the sonographic modifications of tendons have received less attention. In this paper we report the results of an ultrasound evaluation, performed during and after plasma injection, in patients with tendinopathy. The sonographic abnormalities and neovascularization were registered in twenty tendons. Three plasma injections (once a week) were performed, and a rehabilitation program was recommended. Pain and patients' satisfaction were evaluated. During the injections plasma spread along the collagen fibers, and an intratendineous cleft produced by the injected volume was observed. At 12 months two tendons regained a normal echotexture, while neovessels were absent in seven. The remaining tendons showed less abnormalities and neovascularization in comparison with baseline. The clinical improvement was earlier and more consistent. The discrepancy between the ultrasound and clinical results may be explained by the peculiar modalities of tendon healing induced by plasma administration.

Indexed as

neovascularizationplatelet rich plasmatendinopathyultrasound

Identifiers

PMID24932444
PMCPMC4049646
OpenAlexW2030623862

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.