ArticleDental research journal2014
Mast cell count in oral reactive lesions: A histochemical study.
Article in Dental research journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- Role of mast cells in the pathogenesis of oral submucous fibrosis: a systematic review and meta-analysis.BMC oral health · 2024Pooled it
- Epulis: A Narrative Review of Epidemiology, Clinical Features, Pathogenesis, and Management.Oral health & preventive dentistry · 2025Review
- A large-cohort study of 2971 cases of epulis: focusing on risk factors associated with recurrence.BMC oral health · 2023Article
- Quantification of mast cells in oral reactive lesions - an immunohistochemical study.Acta bio-medica : Atenei Parmensis · 2022Article
- Giant Peripheral Ossifying Fibroma of the Posterior Mandible-A Rare Case Report.Iranian journal of pathology · 2017Article
- Evaluation of mast cell counts and microvessel density in reactive lesions of the oral cavity.Journal of dental research, dental clinics, dental prospects · 2016Article
- Immunohistochemical Expression of Mast Cell in Oral Reactive Lesions.Journal of dentistry (Shiraz, Iran) · 2015Article
- Quantification of mast cells in nonreactive and reactive lesions of gingiva: A comparative study using toluidine blue and immunohistochemical marker mast cell tryptase.Journal of oral and maxillofacial pathology : JOMFPArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to quantify the number of mast cells in focal reactive hyperplastic lesions of the oral cavity and to compare these two number of mast cells in normal gingival tissues and to correlate their presence with the state of connective tissue changes in reactive lesions and probably suggest a role for mast cells in these lesions. MATERIALS AND
methodsPatient records were retrieved during a 10 year period from 2001 to 2010. Data of all reactive hyperplasias namely focal fibrous hyperplasia, pyogenic granuloma (PG), peripheral ossifying fibroma (POF) and peripheral giant cell granuloma (PGCG) were reviewed and 10 cases seen in the gingiva were selected for each category and stained with 1% toluidine blue for mast cells. Statistical analysis was applied to see the significant differences between the groups and with the normal gingival tissue. One-way ANOVA-F and unpaired t-test was applied and significant differences were seen between the groups at 5% level of significance.
resultsIn this study, mast cell count was maximum in POF and fibrous hyperplasia (FH) followed by cases of PG and PGCG.
conclusionThe number of mast cells was more numerous in POF and FH suggesting that mast cell activation is a characteristic feature of chronic inflammation, a condition that may lead to fibrosis as a result of increased collagen synthesis by fibroblasts.
Indexed as
Identifiers
24932188PMC4052643W37850106What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.