Evidence map›Paper›PMID 24931945›Full record

ArticleThe Journal of physiology2014

CrossTalk opposing view: Weighing the evidence for class A GPCR dimers, the jury is still out.

Nevin A Lambert, Jonathan A Javitch

Abstract read
In one paragraph

Article in The Journal of physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

  1. Review
  2. Article
  3. Disruption of constitutive CXCR4 oligomers impairs oncogenic properties in lymphoid neoplasms.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Heterobivalent Ligand for the Adenosine AJournal of medicinal chemistry · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Oligomerization of G protein-coupled receptors: Still doubted?Progress in molecular biology and translational science · 2020
    Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Nevin A LambertDepartment of Pharmacology and Toxicology, Medical College of Georgia, Georgia Regents University, Augusta, GA, 30912-2300, USA nelambert@gru.edu.
Jonathan A JavitchDepartments of Psychiatry and Pharmacology, College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, 10032, USA.

Funding

Structure of the Dopamine D2-Like Receptor Binding SitesR01MH054137 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI JAVITCH, JONATHAN A · 1995 to 2025
$12.0M
GPCR signaling complexes in living cellsR01GM078319 · NIGMS · AUGUSTA UNIVERSITY · PI LAMBERT, NEVIN ALAN · 2007 to 2017
$2.1M
Molecular Determinants for the Action of PsychostimulantsK05DA022413 · NIDA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI JAVITCH, JONATHAN A · 2007 to 2016
$1.3M
NIDA NIH HHS DA022413NIDA NIH HHS K05 DA022413NIGMS NIH HHS GM078319NIGMS NIH HHS R01 GM078319NIMH NIH HHS MH54137NIMH NIH HHS R01 MH054137
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Protein MultimerizationReceptors, G-Protein-CoupledReceptors, G-Protein-Coupled

Identifiers

PMID24931945
PMCPMC4080927

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.