ArticleThe Journal of urology2014
Current clinical presentation and treatment of localized prostate cancer in the United States.
Article in The Journal of urology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Assessment of non-inferiority with meta-analysis: example of hypofractionated radiation therapy in breast and prostate cancer.Scientific reports · 2020Pooled it
- Randomized Trial of Hypofractionated, Dose-Escalated, Intensity-Modulated Radiation Therapy (IMRT) Versus Conventionally Fractionated IMRT for Localized Prostate Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2018Trial
- Dosimetric Features of Ultra-Hypofractionated Intensity Modulated Proton Therapy for Prostate Cancer.International journal of particle therapy · 2024Article
- Control of the activity of CAR-T cells within tumours via focused ultrasound.Nature biomedical engineering · 2021Article
- Cause of Mortality after Radical Prostatectomy and the Impact of Comorbidity in Men with Prostate Cancer: A Multi-institutional Study in Korea.Cancer research and treatment · 2020Article
- Vasohibin-1 as a novel microenvironmental biomarker for patient risk reclassification in low-risk prostate cancer.Oncotarget · 2018Article
- Trends in Treatment for Prostate Cancer in China: Preliminary Patterns of Care Study in a Single Institution.Journal of Cancer · 2018Article
- A Monte Carlo study of I-125 prostate brachytherapy with gold nanoparticles: dose enhancement with simultaneous rectal dose sparing via radiation shielding.Physics in medicine and biology · 2017Article
- Radiotherapy in prostate cancer treatment: results of the patterns of care study in Korea.Radiation oncology journal · 2017Article
- Editorial: Controversies and Perspectives in the Use of Postoperative Radiotherapy for Prostate Cancer.Frontiers in oncology · 2017Article
- Patient-Level DNA Damage and Repair Pathway Profiles and Prognosis After Prostatectomy for High-Risk Prostate Cancer.JAMA oncology · 2016Article
- Gaps between Evidence and Practice in Postoperative Radiotherapy for Prostate Cancer: Focus on Toxicities and the Effects on Health-Related Quality of Life.Frontiers in oncology · 2016Review
- Article
- A population-based analysis of contemporary patterns of care in younger men (<60 years old) with localized prostate cancer.International urology and nephrology · 2015Article
- Factors influencing prostate cancer patterns of care: An analysis of treatment variation using the SEER database.Advances in radiation oncologyArticle
- Modern-day prostate cancer is not meaningfully associated with lower urinary tract symptoms: Analysis of a propensity score-matched cohort.Canadian Urological Association journal = Journal de l'Association des urologues du CanadaArticle
- The uptake of active surveillance for the management of prostate cancer: A population-based analysis.Canadian Urological Association journal = Journal de l'Association des urologues du CanadaArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
purposeSEER recently released patient Gleason scores at biopsy/transurethral resection of the prostate. For the first time this permits accurate assessment of prostate cancer presentation and treatment according to clinical factors at diagnosis. MATERIALS AND
methodsWe used the SEER database to identify men diagnosed with localized prostate cancer in 2010 who were assigned NCCN(®) risk based on clinical factors. We identified sociodemographic factors associated with high risk disease and analyzed the impact of these factors along with NCCN risk on local treatment.
resultsOf the 42,403 men identified disease was high, intermediate and low risk in 38%, 40% and 22%, respectively. On multivariate analysis patients who were older, nonwhite, unmarried or living in a county with a higher poverty rate were more likely to be diagnosed with high risk disease (each p <0.05). Of the 38,634 men in whom prostate cancer was the first malignancy 23% underwent no local treatment, 40% were treated with prostatectomy, 36% received radiation therapy and 1% underwent local tumor destruction, predominantly cryotherapy. On multivariate analysis patients who were older, black, unmarried or living in a county with a higher poverty rate, or who had low risk disease were less likely to receive local treatment (each p <0.05).
conclusionsOur analysis provides information on the current clinical presentation and treatment of localized prostate cancer in the United States. Nonwhite and older men living in a county with a higher poverty rate were more likely to be diagnosed with high risk disease and less likely to receive local treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.