Evidence map›Paper›PMID 24931670›Full record

ReviewBiochemical and biophysical research communications2014

Mannose metabolism: more than meets the eye.

Vandana Sharma, Mie Ichikawa, Hudson H Freeze

Open access · greenAbstract readReview
In one paragraph

Review in Biochemical and biophysical research communications, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 123 papers.

0numbers the graph read from it
0cells of the map it votes in
123citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

123 citing papers in PubMed, 231 citations in OpenAlex.

  1. Article
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  9. Quantitative Measurement of Hexoses by Betaine Aldehyde Derivatisation.International journal of molecular sciences · 2026
    Article
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  12. Review
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  20. Article

63 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Vandana SharmaSanford-Burnham Medical Research Institute, La Jolla, CA 92037, USA. Electronic address: vsharma@sanfordburnham.org.
Mie IchikawaSanford-Burnham Medical Research Institute, La Jolla, CA 92037, USA.
Hudson H FreezeSanford-Burnham Medical Research Institute, La Jolla, CA 92037, USA.
Sanford Burnham Prebys Medical Discovery Institute · US

Funding

New Congenital Disorders of Glycosylation: Therapy and ModelsR01DK099551 · NIDDK · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI Hudson H. Freeze · 2014 to 2026
$6.7M
Novel Mechanisms of Exercise Training Effects on Glucose HomeostasisR01DK099511 · NIDDK · JOSLIN DIABETES CENTER · PI LAURIE J GOODYEAR · 2014 to 2026
$6.5M
Carbohydrate Deficient Glycoprotein Syndromes: Models and TherapyR01DK055615 · NIDDK · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI FREEZE, HUDSON H. · 1999 to 2013
$4.4M
NIDDK NIH HHS R01 DK055615NIDDK NIH HHS R01 DK099511NIDDK NIH HHS R01DK099511NIDDK NIH HHS R01 DK099551NIDDK NIH HHS R01DK55615
6 · The paper itself

Abstract

Mannose is a simple sugar with a complex life. It is a welcome therapy for genetic and acquired human diseases, but it kills honeybees and blinds baby mice. It could cause diabetic complications. Mannose chemistry, metabolism, and metabolomics in cells, tissues and mammals can help explain these multiple systemic effects. Mannose has good, bad or ugly outcomes depending on its steady state levels and metabolic flux. This review describes the role of mannose at cellular level and its impact on organisms.

Indexed as

AnimalsCongenital Disorders of GlycosylationDietary CarbohydratesDisease Models, AnimalFemaleGene Knockdown TechniquesHumansMannoseMannose-6-Phosphate IsomeraseMetabolic Flux AnalysisMetabolic Networks and PathwaysMetabolomicsMicePhosphotransferases (Phosphomutases)PolysaccharidesPregnancyDietary CarbohydratesMannoseMannose-6-Phosphate IsomerasePhosphotransferases (Phosphomutases)PolysaccharidesCongenital disorders of glycosylationMannoseMetabolismN-glycosylationPhosphomannomutasePhosphomannose isomerase

Identifiers

PMID24931670
PMCPMC4252654
OpenAlexW1984000875

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.