ArticleGait & posture2014
Identification of the neural component of torque during manually-applied spasticity assessments in children with cerebral palsy.
Article in Gait & posture, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Technology-assisted assessment of spasticity: a systematic review.Journal of neuroengineering and rehabilitation · 2022Pooled it
- Quantitative evaluation for spasticity of calf muscle after botulinum toxin injection in patients with cerebral palsy: a pilot study.Journal of neuroengineering and rehabilitation · 2016Trial
- Good to excellent reliability of instrumented ankle passive resistance and strength measurements in children.Frontiers in pediatrics · 2026Article
- Shear wave elastography in the assessment of gastrocnemius spastic muscle elasticity: influences of ankle position and muscle contraction.European journal of physical and rehabilitation medicine · 2025Observational
- Exploration of the triceps surae muscle in ambulatory children with cerebral palsy using instrumented measurements of stiffness and diffusion tensor magnetic resonance imaging for muscle architecture.BMC musculoskeletal disorders · 2024Observational
- Neuromuscular impairments of cerebral palsy: contributions to gait abnormalities and implications for treatment.Frontiers in human neuroscience · 2024Article
- Examining the role of intrinsic and reflexive contributions to ankle joint hyper-resistance treated with botulinum toxin-A.Journal of neuroengineering and rehabilitation · 2023Article
- Time Course of Wrist Hyper-Resistance in Relation to Upper Limb Motor Recovery Early Post Stroke.Neurorehabilitation and neural repair · 2020Article
- Article
- Neurologic Correlates of Gait Abnormalities in Cerebral Palsy: Implications for Treatment.Frontiers in human neuroscience · 2017Review
- Virtual Normalization of Physical Impairment: A Pilot Study to Evaluate Motor Learning in Presence of Physical Impairment.Frontiers in neuroscience · 2017Article
- Linear Parameter Varying Identification of Dynamic Joint Stiffness during Time-Varying Voluntary Contractions.Frontiers in computational neuroscience · 2017Article
- Neuro-musculoskeletal simulation of instrumented contracture and spasticity assessment in children with cerebral palsy.Journal of neuroengineering and rehabilitation · 2016Article
- Diagnosis and Treatment of` Spasticity and Stiff Muscles.EBioMedicine · 2016Article
- Spasticity and its contribution to hypertonia in cerebral palsy.BioMed research international · 2015Review
- The Intra- and Inter-Rater Reliability of an Instrumented Spasticity Assessment in Children with Cerebral Palsy.PloS one · 2015Article
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Clinical assessment of spasticity is compromised by the difficulty to distinguish neural from non-neural components of increased joint torque. Quantifying the contributions of each of these components is crucial to optimize the selection of anti-spasticity treatments such as botulinum toxin (BTX). The aim of this study was to compare different biomechanical parameters that quantify the neural contribution to ankle joint torque measured during manually-applied passive stretches to the gastrocsoleus in children with spastic cerebral palsy (CP). The gastrocsoleus of 53 children with CP (10.9 ± 3.7 y; females n = 14; bilateral/unilateral involvement n = 28/25; Gross Motor Functional Classification Score I-IV) and 10 age-matched typically developing (TD) children were assessed using a manually-applied, instrumented spasticity assessment. Joint angle characteristics, root mean square electromyography and joint torque were simultaneously recorded during passive stretches at increasing velocities. From the CP cohort, 10 muscles were re-assessed for between-session reliability and 19 muscles were re-assessed 6 weeks post-BTX. A parameter related to mechanical work, containing both neural and non-neural components, was compared to newly developed parameters that were based on the modeling of passive stiffness and viscosity. The difference between modeled and measured response provided a quantification of the neural component. Both types of parameters were reliable (ICC > 0.95) and distinguished TD from spastic muscles (p < 0.001). However, only the newly developed parameters significantly decreased post-BTX (p = 0.012). Identifying the neural and non-neural contributions to increased joint torque allows for the development of individually tailored tone management.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.