ArticleNeuron2014
Increases in functional connectivity between prefrontal cortex and striatum during category learning.
Article in Neuron, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 1 of them a synthesis that pooled it.
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Who cites it
69 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Meta-Analysis Suggests Different Neural Correlates for Implicit and Explicit Learning.Neuron · 2017Pooled it
- Addiction history moderates the effect of prefrontal 10-Hz transcranial alternating current stimulation on habitual action selection.Journal of neurophysiology · 2021Trial
- Mechanistic corticostriatal circuit model predicts learning-dependent fMRI dynamics and individual reward bias in humans.bioRxiv : the preprint server for biology · 2026Article
- Impact of stress on EEG functional connectivity during procedural learning.Clinical neurophysiology practice · 2026Article
- Biomimetic model of corticostriatal micro-assemblies discovers a neural code.Nature communications · 2025Article
- Neuroengineering Frontiers: A Selective Review of Neural Interfaces, Brain-Machine Interactions, and Artificial Intelligence in Neurodegenerative Diseases.Applied sciences (Basel, Switzerland) · 2025Article
- Maintenance and transformation of representational formats during working memory prioritization.Nature communications · 2024Article
- Review
- Cognition is an emergent property.Current opinion in behavioral sciences · 2024Article
- Cingulate microstimulation induces negative decision-making via reduced top-down influence on primate fronto-cingulo-striatal network.Nature communications · 2024Article
- Prefrontal signals precede striatal signals for biased credit assignment in motivational learning biases.Nature communications · 2024Article
- Changes in the dopaminergic circuitry and adult neurogenesis linked to reinforcement learning in corvids.Frontiers in neuroscience · 2024Article
- Distinct neural representations during a brain-machine interface and manual reaching task in motor cortex, prefrontal cortex, and striatum.Scientific reports · 2023Article
- Article
- Spatiotemporal proteomic atlas of multiple brain regions across early fetal to neonatal stages in cynomolgus monkey.Nature communications · 2023Article
- Hierarchical categorization learning is associated with representational changes in the dorsal striatum and posterior frontal and parietal cortex.Human brain mapping · 2023Article
- Distinct beta frequencies reflect categorical decisions.Nature communications · 2023Article
- Working Memory Is Complex and Dynamic, Like Your Thoughts.Journal of cognitive neuroscience · 2022Article
- Abstract Encoding of Categorical Decisions in Medial Superior Temporal and Lateral Intraparietal Cortices.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Minocycline Ameliorates Chronic Unpredictable Mild Stress-Induced Neuroinflammation and Abnormal mPFC-HIPP Oscillations in Mice.Molecular neurobiology · 2022Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Functional connectivity between the prefrontal cortex (PFC) and striatum (STR) is thought critical for cognition and has been linked to conditions like autism and schizophrenia. We recorded from multiple electrodes in PFC and STR while monkeys acquired new categories. Category learning was accompanied by an increase in beta band synchronization of LFPs between, but not within, the PFC and STR. After learning, different pairs of PFC-STR electrodes showed stronger synchrony for one or the other category, suggesting category-specific functional circuits. This category-specific synchrony was also seen between PFC spikes and STR LFPs, but not the reverse, reflecting the direct monosynaptic connections from the PFC to STR. However, causal connectivity analyses suggested that the polysynaptic connections from STR to the PFC exerted a stronger overall influence. This supports models positing that the basal ganglia "train" the PFC. Category learning may depend on the formation of functional circuits between the PFC and STR.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.