Evidence map›Paper›PMID 24930532›Full record

Trial reportAmerican journal of respiratory and critical care medicine2014

Plasma complement levels are associated with primary graft dysfunction and mortality after lung transplantation.

Rupal J Shah, Amir M Emtiazjoo, Joshua M Diamond, Patricia A Smith, David W Roe, Keith M Wille, Jonathan B Orens, Lorraine B Ware, Ann Weinacker, Vibha N Lama and 8 more

Abstract readClinical TrialLetter
In one paragraph

Trial report in American journal of respiratory and critical care medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 34 citations in OpenAlex.

  1. Complement activation in kidney transplantation.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026
    Review
  2. Article
  3. Review
  4. Emerging roles for complement in lung transplantation.The Journal of clinical investigation · 2025
    Review
  5. Review
  6. Temporal correlation between postreperfusion complement deposition and severe primary graft dysfunction in lung allografts.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Primary graft dysfunction: what we know.Journal of thoracic disease · 2021
    Review
  11. A novel injury site-natural antibody targeted complement inhibitor protects against lung transplant injury.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021
    Article
  12. Review
  13. Sterile inflammation in thoracic transplantation.Cellular and molecular life sciences : CMLS · 2021
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 12 institutions in 1 country.

Rupal J Shah1 University of Pennsylvania Philadelphia, Pennsylvania.
Amir M Emtiazjoo
Joshua M Diamond
Patricia A Smith
David W Roe
Keith M Wille
Jonathan B Orens
Lorraine B Ware
Ann Weinacker
Vibha N Lama
Sangeeta M Bhorade
Scott M Palmer
Maria Crespo
David J Lederer
Edward Cantu
George J Eckert
Jason D Christie
David S Wilkes
Indiana University School of MedicineUniversity of Pennsylvania · USColumbia University · USDuke University · USJohns Hopkins University · USNorthwestern University · USStanford Medicine · USUniversity of Alabama at Birmingham · USUniversity of Michigan · USUniversity of Pittsburgh · USUniversity of Pittsburgh Medical Center · USVanderbilt University · US

Funding

TRAINING IN PULMONARY IMMUNOLOGYT32HL007586 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI MEYER, NUALA JENNINGS · 1985 to 2025
$8.8M
Transgenic Mouse CoreP01AI084853 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI GREENSPAN, DANIEL S · 2010 to 2014
$7.7M
Clinical Risk Factors for Primary Graft DysfunctionR01HL087115 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CHRISTIE, JASON D · 2007 to 2017
$7.1M
Genetics of primary graft dysfunctionR01HL081619 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CHRISTIE, JASON D · 2007 to 2011
$3.9M
Obesity, Inflammation, and Lung Injury After Lung TransplantationR01HL114626 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CHRISTIE, JASON D, LEDERER, DAVID J. · 2013 to 2016
$3.1M
Role of anti-Col (V) immunity in primary graft dysfunctionR01HL096845 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CHRISTIE, JASON D, WILKES, DAVID S · 2010 to 2013
$2.2M
Mentored Patient Oriented Research in Lung TransplantationK24HL115354 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CHRISTIE, JASON D · 2012 to 2021
$1.2M
Lung Transplant donor: prediction, evaluation, and mechanismK23HL116656 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CANTU, EDWARD · 2013 to 2017
$872k
NHLBI NIH HHS HL081619NHLBI NIH HHS HL087115NHLBI NIH HHS HL096845NHLBI NIH HHS HL 114626NHLBI NIH HHS HL115354NHLBI NIH HHS K23 HL116656NHLBI NIH HHS K24 HL115354NHLBI NIH HHS R01 HL081619NHLBI NIH HHS R01 HL087115NHLBI NIH HHS R01 HL096845NHLBI NIH HHS R01 HL114626NHLBI NIH HHS T32 HL007568NHLBI NIH HHS T32 HL007586NIAID NIH HHS P01 AI084853NIAID NIH HHS P01AI084853
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnaphylatoxinsBiomarkersFemaleHumansLung TransplantationMalePrimary Graft DysfunctionProportional Hazards ModelsProspective StudiesAnaphylatoxinsBiomarkers

Identifiers

PMID24930532
PMCPMC4226014
OpenAlexW2051545456

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.