ArticleChemical communications (Cambridge, England)2014
Differences in heterocycle basicity distinguish homocysteine from cysteine using aldehyde-bearing fluorophores.
Article in Chemical communications (Cambridge, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 68 citations in OpenAlex.
- Biosynthesis of Oxetanocin-A Includes a BBiochemistry · 2021Article
- The chronological evolution of small organic molecular fluorescent probes for thiols.Chemical science · 2020Review
- High-efficiency dynamic sensing of biothiols in cancer cells with a fluorescent β-cyclodextrin supramolecular assembly.Chemical science · 2020Article
- Fluorescent Probes with Multiple Binding Sites for the Discrimination of Cys, Hcy, and GSH.Angewandte Chemie (International ed. in English) · 2017Review
- pH-Dependent Fluorescent Probe That Can Be Tuned for Cysteine or Homocysteine.Organic letters · 2017Article
- Fluorescein Tri-Aldehyde Promotes the Selective Detection of Homocysteine.Journal of fluorescence · 2016Article
- Synthesis and Application of an Aldazine-Based Fluorescence Chemosensor for the Sequential Detection of Cu²⁺ and Biological Thiols in Aqueous Solution and Living Cells.Sensors (Basel, Switzerland) · 2016Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
We report the detection of homocysteine over cysteine based upon characteristic differences between 5- and 6-membered heterocyclic amines formed upon reaction with aldehyde-bearing compounds. Homocysteine-derived thiazinane-4-carboxylic acids are more basic than cysteine-derived thiazolidines-4-carboxylic acids. Fluorescence enhancement in response to homocysteine is achieved by tuning pH and excitation wavelength.
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