Evidence map›Paper›PMID 24929847›Full record

ReviewInternational journal of hematology2014

The role of microRNAs in lymphopoiesis.

Timothy M Johanson, Jarrod P J Skinner, Amit Kumar, Yifan Zhan, Andrew M Lew, Mark M W Chong

Open access · bronzeAbstract readReview
PubMed Publisher
In one paragraph

Review in International journal of hematology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Epigenetic Alterations in Inborn Errors of Immunity.Journal of clinical medicine · 2022
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. microRNA-dependent temporal gene expression in the ureteric bud epithelium during mammalian kidney development.Developmental dynamics : an official publication of the American Association of Anatomists · 2015
    Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Timothy M JohansonSt Vincent's Institute of Medical Research, Fitzroy, VIC, Australia.
Jarrod P J Skinner
Amit Kumar
Yifan Zhan
Andrew M Lew
Mark M W Chong
St Vincents Institute of Medical Research · AUWalter and Eliza Hall Institute of Medical Research · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The immune system is composed of a diverse range of cell types, each with a distinct function. It can be broadly divided into the lymphoid (T, B, NK, etc.) and myeloid (monocyte, granulocyte, etc.) arms. Lymphopoiesis, the development and differentiation of lymphoid lineages, has been studied extensively for decades. For example, the influence of extracellular signals, signaling pathways and transcription factors has already been well documented. However, the importance of microRNAs has been highlighted by a surge of studies in recent years. In this review, we will discuss what is currently known about the role of microRNAs in lymphopoiesis, from the hematopoietic stem cell through to the differentiation of mature lymphocytes including thymic development, helper and regulatory T cells, fate determination of B cells and dendritic cells.

Indexed as

AnimalsB-LymphocytesCell DifferentiationCell LineageDEAD-box RNA HelicasesDendritic CellsEpigenesis, GeneticGranulocytesHematopoietic Stem CellsHumansLymphopoiesisMicroRNAsRibonuclease IIISignal TransductionT-LymphocytesDEAD-box RNA HelicasesDICER1 protein, humanMicroRNAsRibonuclease III

Identifiers

PMID24929847
OpenAlexW1993786760

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.