Evidence map›Paper›PMID 24929442›Full record

ArticleEuropean journal of radiology2014

The detection of coronary stiffness in cardiac allografts using MR imaging.

Kai Lin, Donald M Lloyd-Jones, Kirsi Taimen, Ying Liu, Xiaoming Bi, Debiao Li, James C Carr

Open access · greenAbstract read
In one paragraph

Article in European journal of radiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kai LinDepartment of Radiology, Northwestern University, 737 N Michigan Avenue, Suite 1600, Chicago, IL 60611, United States. Electronic address: kai-lin@northwestern.edu.
Donald M Lloyd-JonesDepartment of Preventive Medicine, Northwestern University, 680 N Lake Shore Drive, Suite 1400, Chicago, IL 60611, United States.
Kirsi TaimenDepartment of Radiology, Northwestern University, 737 N Michigan Avenue, Suite 1600, Chicago, IL 60611, United States.
Ying LiuDepartment of Radiology, Northwestern University, 737 N Michigan Avenue, Suite 1600, Chicago, IL 60611, United States.
Xiaoming BiCardiovascular MR R&D, Siemens Healthcare, 737 N Michigan Avenue, Suite 1600, Chicago, IL 60611, United States.
Debiao LiDepartment of Radiology, Northwestern University, 737 N Michigan Avenue, Suite 1600, Chicago, IL 60611, United States.
James C CarrDepartment of Radiology, Northwestern University, 737 N Michigan Avenue, Suite 1600, Chicago, IL 60611, United States.
Northwestern University · USSiemens Healthcare (United States) · US

Funding

Chicago Healthy Aging Low Risk MRI Angiography (CHARISMA) StudyR01HL089695 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CARR, JAMES, LLOYD-JONES, DONALD M · 2009 to 2012
$1.8M
NHLBI NIH HHS R01 HL089695
6 · The paper itself

Abstract

objectiveTo test the hypothesis that biomechanical changes are quantitatively related to morphological features of coronary arteries in heart transplant (HTx) recipients. MATERIALS AND

methodsWith IRB approval, three-dimensional (3D) magnetic resonance (MR) angiography and two-dimensional (2D) black-blood stead-state free precession (SSFP) MR imaging were performed to image coronary arteries of 36 HTx patients. Contours of coronary wall were manually drawn. For each coronary segment, coronary wall thickness, wall area, lumen area (in systole and diastole) were acquired. Coronary distensibility index (CDI) and the percent of the coronary wall occupying the vessel area (PWOV) were calculated.

resultsThere are totally 98 coronary segments eligible for quantitative analysis from 27 HTx patients. The CDI is 4.90 ± 2.44 mmHg(-1). The mean wall thickness is 1.49 ± 0.24 mm and the PWOV is 74.6% ± 7.5%. CDI has moderate correlations with wall thickness (r=-0.531, P<0.001) and with PWOV (R=-0.435, P<0.001).

conclusionsDetected with coronary MR imaging, CDI is quantitatively correlated with the morphological features of the coronary artery in HTx patients. Coronary stiffness has the potential to become an alternative imaging biomarker for the quantitative assessment of the status of cardiac allografts.

Indexed as

Heart TransplantationBiomechanical PhenomenaCoronary VesselsFemaleHumansImage Interpretation, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance AngiographyMaleMiddle AgedVascular StiffnessCoronary stiffnessHeart transplantationMagnetic resonance imaging

Identifiers

PMID24929442
PMCPMC4151319
OpenAlexW2081513870

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.