ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2014
Added benefit of nucleic acid amplification testing for the diagnosis of Trichomonas vaginalis among men and women attending a sexually transmitted diseases clinic.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- Sexually Transmitted Infections Treatment Guidelines, 2021.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2021Guideline
- A Guide to Utilization of the Microbiology Laboratory for Diagnosis of Infectious Diseases: 2018 Update by the Infectious Diseases Society of America and the American Society for Microbiology.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Guideline
- Molecular Diagnosis ofJournal of tropical medicine · 2026Review
- Evaluating the epidemiology of vaginitis in a contemporary cohort: a population-based study.Frontiers in public health · 2024Article
- Trichomonas vaginalis Detection in Urogenital Specimens from Symptomatic and Asymptomatic Men and Women by Use of the cobas TV/MG Test.Journal of clinical microbiology · 2021Article
- Molecular epidemiology and socio-demographic risk factors of sexually transmitted infections among women in Lebanon.BMC infectious diseases · 2020Article
- Trichomonas vaginalis Virus Among Women With Trichomoniasis and Associations With Demographics, Clinical Outcomes, and Metronidazole Resistance.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019Article
- Increase Trichomonas vaginalis detection based on urine routine analysis through a machine learning approach.Scientific reports · 2019Article
- Is It Time to Stop Using Single-dose Oral Metronidazole for the Treatment of Trichomoniasis in Women?Sexually transmitted diseases · 2019Article
- Prevalence and Correlates of Trichomonas vaginalis Infection Among Men and Women in the United States.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Article
- Why Does Trichomonas vaginalis Continue to be a "Neglected" Sexually Transmitted Infection?Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Article
- Clinical Evaluation of the Cepheid Xpert TV Assay for Detection of Trichomonas vaginalis with Prospectively Collected Specimens from Men and Women.Journal of clinical microbiology · 2018Article
- Strategies for Prevention and Treatment of Trichomonas vaginalis Infections.Clinical microbiology reviews · 2017Review
- Combined Testing for Chlamydia, Gonorrhea, and Trichomonas by Use of the BD Max CT/GC/TV Assay with Genitourinary Specimen Types.Journal of clinical microbiology · 2017Article
- Epidemiology of Trichomoniasis in South Korea and Increasing Trend in Incidence, Health Insurance Review and Assessment 2009-2014.PloS one · 2016Article
- Structural community factors and sub-optimal engagement in HIV care among low-income women in the Deep South of the USA.Culture, health & sexuality · 2016Article
- Overdiagnosis of Urinary Tract Infection and Underdiagnosis of Sexually Transmitted Infection in Adult Women Presenting to an Emergency Department.Journal of clinical microbiology · 2015Observational
- Prevalence of Trichomonas vaginalis by PCR in men attending a primary care urology clinic in South Korea.The Korean journal of parasitology · 2014Article
- Infectious disease: New Trichs: screening and therapy.Nature reviews. Urology · 2014Article
- Molecular Epidemiologic Study of Male Trichomoniasis in Hamadan, Western Iran.Iranian journal of parasitologyArticle
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTrichomonas vaginalis (TV) is the most common nonviral sexually transmitted infection (STI) in the world. However, TV is not a reportable STI and, with the exception of HIV-positive women, there are no guidelines for screening in women or men. The objective of this study was to determine the added value of nucleic acid amplification tests (NAATs) for detection of TV in men and women at high risk for infection as well as correlates of infection.
methodsThis was a review of clinical and laboratory data of men and women presenting to the Jefferson County Department of Health Sexually Transmitted Diseases (STD) Clinic and receiving a TV NAAT.
resultsDuring 2012-2013, 6335 patients (3821 women and 2514 men) received a TV NAAT on endocervical, urethral, or urine specimens. Overall TV prevalence was 20.2%; 27.0% in women and 9.8% in men. Correlates of TV among men included age >40 years, African American race, and ≥5 polymorphonuclear cells per high-power field on urethral Gram stain. Age >40 years, African American race, leukorrhea on wet mount, elevated vaginal pH, positive whiff test, and concurrent gonococcal infection were positively associated with TV among women. TV NAAT detected approximately one-third more infections among women than wet mount alone.
conclusionsTV prevalence among men and women was high in this study, suggesting that both groups should be routinely screened, including those aged >40 years. Improved detection of TV by routine implementation of NAATs should result in better control of this common, treatable STI.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.