ArticleSurgical endoscopy2014
Laparoscopy-assisted versus open colectomy for treatment of colon cancer in the elderly: morbidity and mortality outcomes in 545 patients.
Article in Surgical endoscopy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 5 of them syntheses that pooled it.
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Who cites it
40 citing papers in PubMed, 5 syntheses or guidelines pooled it, 70 citations in OpenAlex.
- EAES/SAGES evidence-based recommendations and expert consensus on optimization of perioperative care in older adults.Surgical endoscopy · 2024Guideline
- Short-term outcomes of colorectal cancer surgery in patients with dialysis: a systematic review and meta-analysis.Langenbeck's archives of surgery · 2023Pooled it
- Laparoscopic surgery for T4 colon cancer: a systematic review and meta-analysis.Surgical endoscopy · 2017Pooled it
- Colorectal cancer surgery in the very elderly patient: a systematic review of laparoscopic versus open colorectal resection.International journal of colorectal disease · 2017Pooled it
- Laparoscopic colorectal resection versus open colorectal resection in octogenarians: a systematic review and meta-analysis of safety and efficacy.Techniques in coloproctology · 2016Pooled it
- Long-term results of a randomized study comparing open surgery and laparoscopic surgery in elderly colorectal cancer patients (Eld Lap study).Surgical endoscopy · 2021Trial
- Midterm follow-up of a randomized trial of open surgery versus laparoscopic surgery in elderly patients with colorectal cancer.Surgical endoscopy · 2017Trial
- Safety and feasibility of D3 lymph node dissection in oldest-old patients undergoing colorectal cancer surgery: a multi-institutional, retrospective analysis.Techniques in coloproctology · 2025Article
- Preoperative Albumin-bilirubin Score and Colon Inflammatory Index Predict the Prognosis in Colorectal Cancer Patients: A Retrospective Study.Journal of the anus, rectum and colon · 2025Article
- Article
- Surgical and Oncological Outcome of Laparoscopic Resection of Colorectal Cancers: A Single-Center Experience.Cureus · 2024Article
- Prediction of postoperative infectious complications in elderly patients with colorectal cancer: a study based on improved machine learning.BMC medical informatics and decision making · 2024Article
- The influence of serum cholinesterase levels and sarcopenia on postoperative infectious complications in colorectal cancer surgery.Surgery today · 2023Article
- Variations in colorectal cancer pattern of care by age and comorbidity in South Australia.Cancer medicine · 2023Article
- Frailty Assessment and Prehabilitation as Part of a PeRioperative Evaluation and Planning (PREP) Program for Patients Undergoing Colorectal Surgery.Clinics in colon and rectal surgery · 2023Review
- Should be a locally advanced colon cancer still considered a contraindication to laparoscopic resection?Surgical endoscopy · 2022Article
- The impact of low serum cholinesterase levels on survival in patients with colorectal cancer.International journal of colorectal disease · 2022Article
- Article
- What Should We Recommend for Colorectal Cancer Screening in Adults Aged 75 and Older?Current oncology (Toronto, Ont.) · 2021Review
- Surgical Considerations for Older Adults With Cancer: A Multidimensional, Multiphase Pathway to Improve Care.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2021Review
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAdvanced age is a risk factor of major abdominal surgery due to diminished functional reserve and increased comorbidity. Laparoscopy-assisted colectomy is a well-established procedure in colon cancer surgery. The aim of this study was to compare early outcome of elective laparoscopy surgery and open colectomy in colon cancer patients according to age.
methodsA total of 545 patients with colonic adenocarcinoma underwent elective surgery between 2005 and 2009. There were 277 patients in the laparoscopic group and 268 in the open. Patient characteristics in both groups were homogeneous and further stratified into three subgroups by age: <75, between 75-84, and ≥ 85 years. Main outcome measures were early morbidity, mortality, and hospital stay.
resultsOpen surgery group showed a higher overall morbidity rate (37.3 vs. 21.6%, P = 0.001), medical complications (16.4 vs. 10.5%, P = 0.033), surgical complications (23.5 vs. 15.5%, P = 0.034), and mortality (6.7 vs. 3.2%, P = 0.034). The overall morbidity rate difference between open and laparoscopy approach disappeared in the oldest group (≥ 85 years old). Surgical site infections rate was inferior for patients <75 years old in laparoscopy group compared with open. Mortality was also significantly inferior in laparoscopy group in younger patients (<75 years, 0 vs. 3%, P = 0.038). Mean hospital stay was shorter for patients in <75 and 75-84 groups with laparoscopic approach (7.8 vs. 11.4 days and 10 vs. 14.3, respectively, P = 0.001) as compared with those who underwent open surgery, but these differences disappeared in patients aged ≥ 85 years.
conclusionLaparoscopy-assisted colectomy in patients underwent elective surgical resections for colon cancer showed advantages in rate of early complications in patients younger than 85 years of age and was found to be as safe and well tolerated as open surgery in patients over 85 years of age.
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