Evidence map›Paper›PMID 24927950›Full record

ArticleIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2014

Acid-fast bacilli culture positivity and drug resistance in abdominal tuberculosis in Mumbai, India.

Hrishikesh Samant, Devendra Desai, Philip Abraham, Anand Joshi, Tarun Gupta, Camilla Rodrigues, Siji George

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In one paragraph

Article in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Gastrointestinal tuberculosis: A systematic review of epidemiology, presentation, diagnosis and treatment.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Pooled it
  4. Review
  5. Article
  6. Article
  7. Review
  8. Differentiating Crohn's disease from intestinal tuberculosis.World journal of gastroenterology · 2019
    Review
  9. Do additional colonoscopic biopsies increase the yield of Mycobacterium tuberculosis culture in suspected ileo-colonic tuberculosis?Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2018
    Article
  10. Drug resistance in intestinal tuberculosis: A reason to worry?JGH open : an open access journal of gastroenterology and hepatology · 2017
    Article
  11. Article
  12. Hepatic and Intra-abdominal Tuberculosis: 2016 Update.Current infectious disease reports · 2016
    Review
  13. Acid-fast bacilli culture positivity and drug resistance in abdominal tuberculosis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2015
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hrishikesh SamantDivision of Gastroenterology, P D Hinduja National Hospital and Medical Research Centre, Swatantrya Veer Savarkar Marg, Mahim West, Mumbai, 400 016, India.
Devendra Desai
Philip Abraham
Anand Joshi
Tarun Gupta
Camilla Rodrigues
Siji George
National Hospital · INP. D. Hinduja Hospital and Medical Research Centre · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimCulture positivity for Mycobacterium tuberculosis complex (MTB) in abdominal tuberculosis (TB) using Lowenstein Jensen medium and Bactec system varies from 25 % to 36 %. Data on the prevalence of drug resistance in primary abdominal TB is scant. Our aim was to study the acid-fast bacilli (AFB) culture positivity rate in primary abdominal TB using Bactec Mycobacterial Growth Indicator Tubes (MGIT) system and the prevalence of drug resistance in these patients.

methodRecords of patients with abdominal TB (diagnosed on clinical features, endoscopy, histology, microbiology) seen during the period 2008 to 2013 were retrieved from the Gastroenterology and Microbiology departments. Patients with extra-abdominal TB (five pulmonary, two nodal), adnexal (one), and HIV (one) were excluded from analysis.

resultsOf 61 patients, 31 (50.8 %) had a positive AFB culture. In the 30 culture-negative patients, histology showed non-caseating granulomas in 25 patients. Drug sensitivity pattern was analyzed in 18 patients; resistance was detected in eight (14.3 % of all patients and 44.4 % of patients in whom drug sensitivity was done) including three (5.4 % of all subjects and 16.6 % in whom drug sensitivity was available) who were multidrug-resistant.

conclusionsThe rate of AFB culture positivity in primary abdominal TB was 50.8 % using Bactec MGIT. Likelihood of drug resistance was seen in 14.3 %, of whom 5.4 % were multidrug-resistant.

Indexed as

AdolescentAdultAgedAntitubercular AgentsDrug Resistance, BacterialFemaleHumansIndiaMaleMicrobial Sensitivity TestsMiddle AgedMycobacterium tuberculosisPrevalenceRetrospective StudiesTuberculosis, GastrointestinalYoung AdultAntitubercular Agents

Identifiers

PMID24927950
OpenAlexW1978291233

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.