ArticleBMC plant biology2014
The American cranberry: first insights into the whole genome of a species adapted to bog habitat.
Article in BMC plant biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
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Who cites it
53 citing papers in PubMed.
- Investigating the knowledge, attitude, and practice of cranberry extract supplements among registered pharmacists in Jordan.Scientific reports · 2026Article
- A high-recovery, high-density targeted genotyping platform for cranberry.The plant genome · 2026Article
- First whole genome sequence of a diploid crop wild relative of the Andean tuber "oca": Annotation and comparative genomic analysis of Oxalis oulophora.The plant genome · 2026Article
- Interspecific hybridization history ofHorticulture research · 2025Article
- A public mid-density genotyping platform for cultivated cranberry (Vaccinium macrocarpon Aiton).The plant genome · 2025Article
- Improving the Antioxidant Potential of Berry Crops Through Genomic Advances and Modern Agronomic and Breeding Tools.Biotech (Basel (Switzerland)) · 2025Review
- Characterization of theInternational journal of molecular sciences · 2025Article
- Genome report: First reference genome of Vaccinium floribundum Kunth, an emblematic Andean species.G3 (Bethesda, Md.) · 2024Article
- Of buds and bits: a meta-QTL study identifies stable QTL for berry quality and yield traits in cranberry mapping populations (Frontiers in plant science · 2024Article
- The biosynthesis, degradation, and function of cell wall β-xylosylated xyloglucan mirrors that of arabinoxyloglucan.The New phytologist · 2023Article
- Cranberry fruit epicuticular wax benefits and identification of a wax-associated molecular marker.BMC plant biology · 2023Article
- Two genes, ANS and UFGT2, from Vaccinium spp. are key steps for modulating anthocyanin production.Frontiers in plant science · 2023Article
- Genomic and Bioinformatic Resources for Perennial Fruit Species.Current genomics · 2022Review
- Contrasting a reference cranberry genome to a crop wild relative provides insights into adaptation, domestication, and breeding.PloS one · 2022Article
- Conservation and Diversity of miR166 Family Members From Highbush Blueberry (Frontiers in genetics · 2022Article
- There and back again; historical perspective and future directions forHorticulture research · 2022Article
- High-quality reference genome and annotation aids understanding of berry development for evergreen blueberry (Vaccinium darrowii).Horticulture research · 2021Article
- Chromosome-Level Genome Assembly of the American Cranberry (Frontiers in plant science · 2021Article
- Cranberry Extract for Symptoms of Acute, Uncomplicated Urinary Tract Infection: A Systematic Review.Antibiotics (Basel, Switzerland) · 2020Review
- Annotated genome sequences of the carnivorous plant Roridula gorgonias and a non-carnivorous relative, Clethra arborea.BMC research notes · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe American cranberry (Vaccinium macrocarpon Ait.) is one of only three widely-cultivated fruit crops native to North America- the other two are blueberry (Vaccinium spp.) and native grape (Vitis spp.). In terms of taxonomy, cranberries are in the core Ericales, an order for which genome sequence data are currently lacking. In addition, cranberries produce a host of important polyphenolic secondary compounds, some of which are beneficial to human health. Whereas next-generation sequencing technology is allowing the advancement of whole-genome sequencing, one major obstacle to the successful assembly from short-read sequence data of complex diploid (and higher ploidy) organisms is heterozygosity. Cranberry has the advantage of being diploid (2n = 2x = 24) and self-fertile. To minimize the issue of heterozygosity, we sequenced the genome of a fifth-generation inbred genotype (F ≥ 0.97) derived from five generations of selfing originating from the cultivar Ben Lear.
resultsThe genome size of V. macrocarpon has been estimated to be about 470 Mb. Genomic sequences were assembled into 229,745 scaffolds representing 420 Mbp (N50 = 4,237 bp) with 20X average coverage. The number of predicted genes was 36,364 and represents 17.7% of the assembled genome. Of the predicted genes, 30,090 were assigned to candidate genes based on homology. Genes supported by transcriptome data totaled 13,170 (36%).
conclusionsShotgun sequencing of the cranberry genome, with an average sequencing coverage of 20X, allowed efficient assembly and gene calling. The candidate genes identified represent a useful collection to further study important biochemical pathways and cellular processes and to use for marker development for breeding and the study of horticultural characteristics, such as disease resistance.
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