ArticleProceedings of the National Academy of Sciences of the United States of America2014
Badger responses to small-scale culling may compromise targeted control of bovine tuberculosis.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 78 citations in OpenAlex.
- Absence of effects of widespread badger culling on tuberculosis in cattle.Scientific reports · 2024Article
- Badger Ecology, Bovine Tuberculosis, and Population Management: Lessons from the Island of Ireland.Transboundary and emerging diseases · 2024Review
- Genomic epidemiology ofMicrobial genomics · 2023Article
- Strategies for managing marine disease.Ecological applications : a publication of the Ecological Society of America · 2022Article
- Towards Reverse Vaccinology for Bovine TB: High Throughput Expression of Full Length RecombinantFrontiers in molecular biosciences · 2022Article
- Effect of selective removal of badgers (Epidemiology and infection · 2021Article
- Ecological drivers of African swine fever virus persistence in wild boar populations: Insight for control.Ecology and evolution · 2020Article
- Ecological interventions to prevent and manage zoonotic pathogen spillover.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Review
- Wolves contribute to disease control in a multi-host system.Scientific reports · 2019Article
- Further description of bovine tuberculosis trends in the United Kingdom and the Republic of Ireland, 2003-2015.The Veterinary record · 2018Article
- The bovine tuberculosis cluster in north County Sligo during 2014-16.Irish veterinary journal · 2018Article
- Blood thicker than water: kinship, disease prevalence and group size drive divergent patterns of infection risk in a social mammal.Proceedings. Biological sciences · 2016Article
- Self-disseminating vaccines for emerging infectious diseases.Expert review of vaccines · 2016Review
- Model of Selective and Non-Selective Management of Badgers (Meles meles) to Control Bovine Tuberculosis in Badgers and Cattle.PloS one · 2016Article
- Are All Hosts Created Equal? Partitioning Host Species Contributions to Parasite Persistence in Multihost Communities.The American naturalist · 2015Article
- Herd-level bovine tuberculosis risk factors: assessing the role of low-level badger population disturbance.Scientific reports · 2015Article
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- Spatial Targeting for Bovine Tuberculosis Control: Can the Locations of Infected Cattle Be Used to Find Infected Badgers?PloS one · 2015Article
- Animal health: How to control bovine tuberculosis.Nature · 2014Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Where wildlife disease requires management, culling is frequently considered but not always effective. In the British Isles, control of cattle tuberculosis (TB) is hindered by infection in wild badger (Meles meles) populations. Large-scale badger culling can reduce the incidence of confirmed cattle TB, but these benefits are undermined by culling-induced changes in badger behavior (termed perturbation), which can increase transmission among badgers and from badgers to cattle. Test-vaccinate/remove (TVR) is a novel approach that entails testing individual badgers for infection, vaccinating test-negative animals, and killing test-positive animals. Imperfect capture success, diagnostic sensitivity, and vaccine effectiveness mean that TVR would be expected to leave some infected and some susceptible badgers in the population. Existing simulation models predict that TVR could reduce cattle TB if such small-scale culling causes no perturbation, but could increase cattle TB if considerable perturbation occurs. Using data from a long-term study, we show that past small-scale culling was significantly associated with four metrics of perturbation in badgers: expanded ranging, more frequent immigration, lower genetic relatedness, and elevated prevalence of Mycobacterium bovis, the causative agent of TB. Though we could not reject the hypothesis that culling up to three badgers per social group might avoid perturbation, we also could not reject the hypothesis that killing a single badger prompted detectable perturbation. When considered alongside existing model predictions, our findings suggest that implementation of TVR, scheduled for 2014, risks exacerbating the TB problem rather than controlling it. Ongoing illegal badger culling is likewise expected to increase cattle TB risks.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.