Evidence map›Paper›PMID 24926793›Full record

ArticleCell reports2014

AKAP5 keeps L-type channels and NFAT on their toes.

Manuel F Navedo, Johannes W Hell

Open access · goldAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Sense and specificity in neuronal calcium signalling.Biochimica et biophysica acta · 2015
    Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Manuel F NavedoDepartment of Pharmacology, University of California, Davis, CA 95615, USA. Electronic address: mfnavedo@ucdavis.edu.
Johannes W HellDepartment of Pharmacology, University of California, Davis, CA 95615, USA. Electronic address: jwhell@ucdavis.edu.
University of California, Davis · US

Funding

Calcium Sparklets-Induced Vascular Dysfunction During DiabetesR01HL098200 · NHLBI · UNIVERSITY OF WASHINGTON · PI NAVEDO, MANUEL F · 2010 to 2019
$3.5M
NHLBI NIH HHS R01 HL098200
6 · The paper itself

Abstract

In this issue of Cell Reports, Murphy et al. and Dittmer et al. present exciting new insight into the regulation of Ca2+ influx via the L-type Ca2+ channel Cav1.2 and how increased Ca2+ influx translates into localized activation of the nuclear transcription factor NFAT upon depolarization in neurons.

Indexed as

Signal TransductionTranscriptional ActivationA Kinase Anchor ProteinsAnimalsCalcineurinCalciumCalcium Channels, L-TypeCyclic AMP-Dependent Protein KinasesDendritic SpinesHumansNeuronsNFATC Transcription FactorsA Kinase Anchor ProteinsCalcineurinCalciumCalcium Channels, L-TypeCyclic AMP-Dependent Protein KinasesNFATC Transcription Factors

Identifiers

PMID24926793
PMCPMC7032163
OpenAlexW2001922202

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.