ArticleJournal of global infectious diseases2014
Investigating a community-wide outbreak of hepatitis a in India.
Article in Journal of global infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 49 citations in OpenAlex.
- Expert consensus and recommendations on the live attenuated hepatitis A vaccine and immunization practices in India.Human vaccines & immunotherapeutics · 2025Article
- Use of the Chainchecker application: Uganda's experience during the 2022 Sudan Virus Disease outbreak.PLOS global public health · 2025Article
- Review
- Endemicity change of hepatitis A infection necessitates vaccination in food handlers: An Indian perspective.Human vaccines & immunotherapeutics · 2022Review
- The Clinical Profile of Children With Hepatitis A Infection: An Observational Hospital-Based Study.Cureus · 2022Article
- A Modern Perspective on Vaccinating Healthcare Service Providers in India: A Narrative Review.Infectious diseases and therapy · 2022Review
- Investigating the spatio-temporal variation of hepatitis A in Korea using a Bayesian model.Frontiers in public health · 2022Article
- Nanoemulsions: The rising star of antiviral therapeutics and nanodelivery system-current status and prospects.Current opinion in colloid & interface science · 2021Review
- Hepatitis A Outbreak with the Concurrence ofThe American journal of tropical medicine and hygiene · 2020Article
- Increasing Burden of Hepatitis A in Adolescents and Adults and the Need for Long-Term Protection: A Review from the Indian Subcontinent.Infectious diseases and therapy · 2019Review
- Waterborne & foodborne viral hepatitis: A public health perspective.The Indian journal of medical research · 2019Article
- Methods for generating hypotheses in human enteric illness outbreak investigations: a scoping review of the evidence.Epidemiology and infection · 2019Article
- A study of hepatitis A virus seropositivity among children aged between 1 and 5 years of age: Implications for universal immunization.Medical journal, Armed Forces India · 2019Article
- Suspected spread of hepatitis A virus from a restaurant among adults in rural area of the Kerala state, India.Epidemiology and infection · 2019Article
- Do medical college students living in hostel in India need hepatitis A vaccine?The Indian journal of medical research · 2018Article
- epicontacts: Handling, visualisation and analysis of epidemiological contacts.F1000Research · 2018Article
- Out-of-pocket expenditure due to hepatitis A disease: A study from Kollam district, Kerala, India.The Indian journal of medical research · 2017Article
- Investigation of an Outbreak of Hepatitis A in a Coastal Area, Kerala, Southern India.Journal of primary care & community health · 2016Article
- Viral hepatitis: Indian scenario.Medical journal, Armed Forces India · 2016Article
- Investigation of an Outbreak of Acute Gastroenteritis in Kollam, Kerala, India.Journal of primary care & community health · 2016Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere was an outbreak of acute hepatitis in Mylapore village, Kollam district, Kerala, southern India during February to June 2013. An outbreak investigation was initiated with the objective of describing the epidemiological features of the hepatitis outbreak. MATERIALS AND
methodsHouse-to-house visits were undertaken to identify symptomatic cases. The outbreak was described in terms of person, place and time. Hypothesis was generated based on findings from descriptive study, laboratory investigation of water samples, and environmental observations. A case-control study was designed to test the hypothesis. Chi-square test, univariate analysis, and logistic regression to identify the risk factors associated with hepatitis A infection were done.
resultsLine list generated consisted of 45 cases. Attack rate was the highest among the age group 15-24 years (4.6%) followed by 5-14 years (3.1%). The geographical distribution of the cases suggested a clustering around the water supply through the pipeline and epidemic curve showed a sharp rise in cases suggestive of a common source outbreak. Water samples collected form pipeline showed evidence of fecal contamination and absence of residual chlorine. In the case-control study, having consumed water from the pipeline (odds ratio: 9.01 [95% confidence interval: 2.16-37.61]) was associated with the hepatitis A cases.
conclusionThe time frame of disease occurrence, environmental observations, anecdotal evidences, laboratory results and results of the analytical study indicated the possibility of occurrence of hepatitis A outbreak as a result of pipe water contamination supplied from a bore well. The study warrants establishment of an efficient water quality surveillance system.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.