Trial reportThe British journal of psychiatry : the journal of mental science2015
Gains in employment status following antidepressant medication or cognitive therapy for depression.
Trial report in The British journal of psychiatry : the journal of mental science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Interventions to improve return to work in depressed people.The Cochrane database of systematic reviews · 2020Pooled it
- Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder: Section 2. Psychological Treatments.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2016Pooled it
- Moderators of LGBQ-affirmative cognitive behavioral therapy: ESTEEM is especially effective among Black and Latino sexual minority men.Journal of consulting and clinical psychology · 2023Trial
- Prospective Predictors of Work Limitations in Young Adult Lesbian and Bisexual Women: An Examination of Minority Stress, Trauma Exposure, and Mental Health.Stigma and health · 2023Article
- The Italian consensus conference on psychological therapies for anxiety and depressive disorders: findings and recommendations.Epidemiology and psychiatric sciences · 2022Article
- Clinical research challenges posed by difficult-to-treat depression.Psychological medicine · 2022Review
- Costs associated with depression and obesity among cardiovascular patients: medical expenditure panel survey analysis.BMC health services research · 2021Article
- Moderation, mediation, and moderated mediation.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2019Article
- The Roles of Socioeconomic Status, Occupational Health and Job Rank on the Epidemiology of Different Psychiatric Symptoms in a Sample of UK Workers.Community mental health journal · 2019Article
- Raising Awareness for the Replication Crisis in Clinical Psychology by Focusing on Inconsistencies in Psychotherapy Research: How Much Can We Rely on Published Findings from Efficacy Trials?Frontiers in psychology · 2018Article
- An observational study of duloxetine versus SSRI monotherapy for the treatment of painful physical symptoms in Japanese patients with major depressive disorder: primary analysis.Neuropsychiatric disease and treatment · 2017Article
- A prospective cohort study of depression course, functional disability, and NEET status in help-seeking young adults.Social psychiatry and psychiatric epidemiology · 2016Article
- Making Evidence-Based Psychotherapy More Accessible in Canada.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2016Article
- Employment outcomes one year after bariatric surgery: the role of patient and psychosocial factors.Obesity surgery · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundDepression can adversely affect employment status.
aimsTo examine whether there is a relative advantage of cognitive therapy or antidepressant medication in improving employment status following treatment, using data from a previously reported trial.
methodRandom assignment to cognitive therapy (n = 48) or the selective serotonin reuptake inhibitor paroxetine (n = 93) for 4 months; treatment responders were followed for up to 24 months. Differential effects of treatment on employment status were examined.
resultsAt the end of 28 months, cognitive therapy led to higher rates of full-time employment (88.9%) than did antidepressant medication among treatment responders (70.8%), χ(2) 1 = 5.78, P = 0.02, odds ratio (OR) = 5.66, 95% CI 1.16-27.69. In the shorter-term, the main effect of treatment on employment status was not significant following acute treatment (χ(2) 1 = 1.74, P = 0.19, OR = 1.77, 95% CI 0.75-4.17); however, we observed a site×treatment interaction (χ(2) 1 = 6.87, P = 0.009) whereby cognitive therapy led to a higher rate of full-time employment at one site but not at the other.
conclusionsCognitive therapy may produce greater improvements in employment v. medication, particularly over the longer term.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.