Evidence map›Paper›PMID 24925675›Full record

Trial reportCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2014

Make your own cigarettes: toxicant exposure, smoking topography, and subjective effects.

Bartosz Koszowski, Zachary R Rosenberry, Lauren C Viray, Jennifer L Potts, Wallace B Pickworth

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Nicotine Delivery of a Menthol-Flavored Heat-not-Burn Tobacco Product During Directed Use.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Large Cigars: Smoking Topography and Toxicant Exposure.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2018
    Article
  7. Article
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  11. Article
  12. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Bartosz KoszowskiBattelle Memorial Institute, Human Exposure Assessment Laboratory (HEAL), Baltimore, Maryland. koszowskib@battelle.org.
Zachary R RosenberryBattelle Memorial Institute, Human Exposure Assessment Laboratory (HEAL), Baltimore, Maryland.
Lauren C VirayBattelle Memorial Institute, Human Exposure Assessment Laboratory (HEAL), Baltimore, Maryland.
Jennifer L PottsBattelle Memorial Institute, Human Exposure Assessment Laboratory (HEAL), Baltimore, Maryland.
Wallace B PickworthBattelle Memorial Institute, Human Exposure Assessment Laboratory (HEAL), Baltimore, Maryland.
Battelle · US

Funding

Roll Your Own (RYO) Cigarettes: Prevalence, Smoking Behavior and Toxin ExposureR01CA138973 · NCI · BATTELLE CENTERS/PUB HLTH RES & EVALUATN · PI PICKWORTH, WALLACE BRUCE · 2009 to 2011
$1.3M
NCI NIH HHS R01 CA138973NCI NIH HHS R01CA138973-01
6 · The paper itself

Abstract

backgroundDespite considerable use of make your own (MYO) cigarettes worldwide and increasing use in the United States, relatively little is known about how these cigarettes are smoked and the resultant toxicant exposure.

methodsIn a laboratory study, we compared two types of MYO cigarettes-roll your own (RYO) and personal machine made (PMM)-with factory-made (FM) cigarettes in three groups of smokers who exclusively used RYO (n = 34), PMM (n = 23), or FM (n = 20). Within each group, cigarettes were smoked in three conditions: (i) after confirmed overnight tobacco abstinence; (ii) in an intense smoking paradigm; and (iii) without restrictions. All cigarettes were smoked ad lib through a smoking topography unit.

resultsPlasma nicotine significantly increased after cigarettes in all conditions except PMM in the intense smoking paradigm. Puff volume, puff duration, total puff volume, and puff velocity did not differ between cigarette types but the puffs per cigarette and time to smoke were significantly smaller for RYO compared with PMM and FM. Regardless of the cigarette, participants consumed the first three puffs more vigorously than the last three puffs.

conclusionsDespite the belief of many of their consumers, smoking MYO cigarettes is not a safe alternative to FM cigarettes. Like FM, MYO cigarettes expose their users to harmful constituents of tobacco smoke. Despite differences in size and design their puffing profiles are remarkably similar. IMPACT: These data are relevant to health and regulatory considerations on the MYO cigarettes.

Indexed as

AdultBaltimoreFemaleHumansMaleNicotineSmokingTobacco ProductsTobacco Use DisorderNicotine

Identifiers

PMID24925675
PMCPMC4154992
OpenAlexW2077444298

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.