Evidence map›Paper›PMID 24925624›Full record

SynthesisJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2014

Prognostic value of normal stress myocardial perfusion imaging in diabetic patients: a meta-analysis.

Wanda Acampa, Valeria Cantoni, Roberta Green, Francesca Maio, Stefania Daniele, Carmela Nappi, Valeria Gaudieri, Giorgio Punzo, Mario Petretta, Alberto Cuocolo

Abstract readMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Trial
  2. Article
  3. Prognostic Value of Coronary Flow Capacity byCirculation. Cardiovascular imaging · 2024
    Article
  4. Review
  5. Revascularization of non-culprit lesions: A common dilemma.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  6. The addition of coronary artery calcium to myocardial perfusion: Double or nothing?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  7. Article
  8. Gender differences in outcome in patients with diabetes mellitus.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  9. Review
  10. Prognostic value of one millisievert exercise myocardial perfusion imaging in patients without known coronary artery disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  11. Comparison of ESC and ACC/AHA guidelines for myocardial revascularization: are the differences clinically relevant? The European perspective.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
  12. Review
  13. Review
  14. Review
  15. Immortality time and serial myocardial perfusion imaging: Only those who do not die may repeat the exam.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016
    Article
  16. Screening asymptomatic patients with type 2 diabetes is recommended: Pro.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015
    Article
  17. Review of cardiovascular imaging in The Journal of Nuclear Cardiology in 2014: Part 2 of 2: Myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015
    Review
  18. Predictors of Myocardial Ischemia in Preoperative Oncology Patients Who Underwent Fluorodeoxyglucose-Positron Emission Tomography Study.Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India
    Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wanda AcampaInstitute of Biostructure and Bioimaging, National Council of Research, Naples, Italy.
Valeria Cantoni
Roberta Green
Francesca Maio
Stefania Daniele
Carmela Nappi
Valeria Gaudieri
Giorgio Punzo
Mario Petretta
Alberto Cuocolo

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prognostic value of normal stress myocardial perfusion single-photon emission computed tomography (MPS) in patients with diabetes has only been evaluated in single-center studies of relatively limited sample size. We performed a meta-analysis of published studies, including diabetic patients with known or suspected coronary artery disease (CAD), to assess the predictive value for adverse cardiac ischemic events of normal stress MPS. METHODS AND

resultsStudies published between January 1990 and December 2013 were identified by database search. We included studies using stress MPS to evaluate diabetic patients with known or suspected CAD and providing data on clinical outcomes of non-fatal myocardial infarction or cardiac death with a follow-up time ≥12 months. A total of 14 studies were finally included, recruiting 13,493 patients. The negative predictive value (NPV) for non-fatal myocardial infarction and cardiac death of normal MPS was 94.92% (95% confidence interval 93.67-96.05), during a weighted mean follow-up of 36.24 months, resulting in estimated event rate after a negative test equal to 5.08% (95% confidence interval 3.95-6.33). The corresponding annualized event rate after a negative test was 1.60% (95% confidence interval 1.21-2.04).

conclusionsStress MPS has a high NPV for adverse cardiac events in diabetic patients with known or suspected CAD leading to define a "relatively low-risk" patients category.

Indexed as

ComorbidityCoronary Artery DiseaseDeath, Sudden, CardiacDiabetes MellitusEvidence-Based MedicineExercise TestHumansIncidenceMyocardial Perfusion ImagingPrognosisReproducibility of ResultsRisk AssessmentSensitivity and SpecificitySurvival Rate

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.