ArticleNeuroradiology2014
Differentiating intraparenchymal hemorrhage from contrast extravasation on post-procedural noncontrast CT scan in acute ischemic stroke patients undergoing endovascular treatment.
Article in Neuroradiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.
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50 citing papers in PubMed, 2 syntheses or guidelines pooled it, 83 citations in OpenAlex.
- Diagnostic accuracy of dual-energy computed tomography in the diagnosis of neurological complications after endovascular treatment of acute ischaemic stroke: a systematic review and meta-analysis.The British journal of radiology · 2024Pooled it
- Dual-energy CT for differentiating acute intracranial hemorrhage from contrast staining or calcification: a meta-analysis.Neuroradiology · 2020Pooled it
- A Location-Specific Hyperdense Area Score Predicts Severe Mass Effect after Thrombectomy.Neurocritical care · 2026Article
- Deep learning prediction of contrast extravasation versus intracranial hemorrhage after thrombectomy in patients with acute stroke.BMC medical imaging · 2026Article
- Prognostic significance of contrast staining following mechanical thrombectomy in acute ischaemic stroke.Stroke and vascular neurology · 2025Observational
- CT hyperdensities after recanalization for anterior circulation large vessels occlusion: a predictor for malignant brain edema after ischemic stroke?Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Association Between Early Spontaneous Post-Thrombectomy Blood Pressure Reduction and Clinical Outcomes in Large Vessel Occlusion Stroke.Brain and behavior · 2025Article
- The Effectiveness of Deep Learning in the Differential Diagnosis of Hemorrhagic Transformation and Contrast Accumulation After Endovascular Thrombectomy in Acute Ischemic Stroke Patients.Diagnostics (Basel, Switzerland) · 2025Article
- Contrast enhancement after mechanical thrombectomy: clinical correlations and impact on outcomes.Acta neurologica Belgica · 2025Article
- Intracranial hemorrhage prediction in acute ischemic stroke patients with anterior circulation tandem lesions following endovascular thrombectomy.Frontiers in neurology · 2025Article
- Direct endovascular treatment may be more appropriate for patients with good collateral circulation: a retrospective case-control study.Quantitative imaging in medicine and surgery · 2024Article
- Article
- Incidence, Risk Factors, and Clinical Implications of Subarachnoid Hyperdensities on Flat-Panel Detector CT following Mechanical Thrombectomy in Patients with Anterior Circulation Acute Ischemic Stroke.AJNR. American journal of neuroradiology · 2024Article
- Contrast extravasation mimicking intracerebral and intraventricular hemorrhage after intravenous thrombolytic treatment of ischemic stroke: a case report.BMC neurology · 2024Article
- Quantification of ischemic brain edema after mechanical thrombectomy using dual-energy computed tomography in patients with ischemic stroke.Scientific reports · 2024Article
- Predicting the clinical prognosis of acute ischemic stroke using machine learning: an application of radiomic biomarkers on non-contrast CT after intravascular interventional treatment.Frontiers in neuroinformatics · 2024Article
- The ratio of the maximum density values: a new method for predicting hemorrhagic transformation in acute ischemic stroke patients undergoing mechanical thrombectomy.Frontiers in neurology · 2024Article
- Early antithrombotic therapy in patients with postinterventional cerebral hyperdensity reduces early neurological deterioration after mechanical thrombectomy.BMC neurology · 2023Article
- Article
- Comparative Studies of Cerebral Reperfusion Injury in the Posterior and Anterior Circulations After Mechanical Thrombectomy.Translational stroke research · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThis study aimed to identify the imaging characteristics that can help differentiate intraparenchymal hemorrhage from benign contrast extravasation on post-procedural noncontrast CT scan in acute ischemic stroke patients after endovascular treatment.
methodsWe reviewed the clinical and imaging records of all acute ischemic stroke patients who underwent endovascular treatment in two hospitals over a 3.5-year period. The immediate post-procedural CT scan was evaluated for the presence of hyperdense lesion(s). The average attenuation of the lesion(s) was measured. Intraparenchymal hemorrhage was defined as a persistent hyperdensity visualized on follow-up CT scan, 24 h or greater after the procedure.
resultsOf the 135 patients studied, 74 (55%) patients had hyperdense lesion(s) on immediate post-procedural CT scan. Follow-up scans confirmed the diagnosis of intraparenchymal hemorrhage in 20 of these 74 patients. A receiver operating characteristic analysis showed that the average attenuation of the most hyperdense lesion can differentiate intraparenchymal hemorrhage from contrast extravasation with an area under the curve of 0.78 (p = 0.001). An average attenuation of <50 Hounsfield units (HU) in the most visually hyperattenuating hyperdense lesion had 100 % specificity and 56% sensitivity for identification of contrast extravasations. Petechial hyperdensity was seen in 46/54 (85%) patients with contrast extravasation versus 9/20 (45%) patients with intraparenchymal hemorrhage on the immediate post-procedural CT scan (p < 0.001).
conclusionAn average attenuation <50 HU of the most hyperattenuating hyperdense parenchymal lesion on immediate post-procedural CT scan was very specific for differentiating contrast extravasation from intraparenchymal hemorrhage in acute ischemic stroke patients after endovascular treatment.
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