ArticleDigestive diseases and sciences2014
Prevalence of uninvestigated dyspepsia and gastroesophageal reflux disease in Korea: a population-based study using the Rome III criteria.
Article in Digestive diseases and sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Insight into global burden of gastroesophageal reflux disease: Understanding its reach and impact.World journal of gastrointestinal pharmacology and therapeutics · 2025Review
- Potential Risks Associated With Long-term Use of Proton Pump Inhibitors and the Maintenance Treatment Modality for Patients With Mild Gastroesophageal Reflux Disease.Journal of neurogastroenterology and motility · 2024Review
- Gastroesophageal reflux disease in Sri Lanka: An island-wide epidemiological survey assessing the prevalence and associated factors.PLOS global public health · 2024Article
- Feasibility Study on Endoscopic Balloon-Assisted Laser Treatment (EBLT) of Gastroesophageal Reflux Disease (GERD) in In Vivo Porcine Model.Biomedicines · 2023Article
- Herbal Medicine Yukgunja-Tang for Functional Dyspepsia: A Protocol for a Randomized, Controlled, Multicenter Clinical Trial.Healthcare (Basel, Switzerland) · 2023Article
- Clinical Implications of the Gastroesophageal Reflux Disease Questionnaire and Reflux Symptom Index in Patients With Suspected Laryngopharyngeal Reflux Symptoms.Journal of neurogastroenterology and motility · 2022Article
- Epidemiology and Clinical Characteristics Based on the Rome III and IV Criteria of Japanese Patients with Functional Dyspepsia.Journal of clinical medicine · 2022Article
- The Korean Self-evaluation Questionnaire for Functional Dyspepsia.Journal of neurogastroenterology and motility · 2022Article
- Development and Validity Assessment of a Self-evaluation Questionnaire for Functional Dyspepsia: A Multicenter Prospective Study in Korea.Journal of neurogastroenterology and motility · 2022Article
- Prevalence, symptoms and risk factor profile of rumination syndrome and functional dyspepsia: a population-based study.Alimentary pharmacology & therapeutics · 2021Article
- The prevalence of uninvestigated dyspepsia and the association of physical exercise with quality of life of uninvestigated dyspepsia patients in Indonesia: An internet-based survey.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2021Article
- The Usefulness of Esophageal Baseline Impedance Levels for the Diagnosis of Nonerosive Reflux Disease and the Proper Time for Measurement in Endoscopy-negative Korean Patients With Esophageal or Supraesophageal Symptoms.Journal of neurogastroenterology and motility · 2020Article
- Anti-reflux Surgery Versus Proton Pump Inhibitors for Severe Gastroesophageal Reflux Disease: A Cost-Effectiveness Study in Korea.Journal of neurogastroenterology and motility · 2020Article
- Treatment Pattern and Economic Burden of Refractory Gastroesophageal Reflux Disease Patients in Korea.Journal of neurogastroenterology and motility · 2020Article
- Validation of the Korean Version of the Gastroesophageal Reflux Disease Questionnaire for the Diagnosis of Gastroesophageal Reflux Disease.Journal of neurogastroenterology and motility · 2019Article
- Article
- Gastroesophageal reflux disease and its related factors among women of reproductive age: Korea Nurses' Health Study.BMC public health · 2018Article
- The Degree of Disease Knowledge in Patients with Gastroesophageal Reflux Disease: A Multi-center Prospective Study in Korea.Journal of neurogastroenterology and motility · 2017Article
- Korean Gastric Cancer Association Nationwide Survey on Gastric Cancer in 2014.Journal of gastric cancer · 2016Review
- Functional dyspepsia: new insights into pathogenesis and therapy.The Korean journal of internal medicine · 2016Review
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsThere have been few population-based studies on the prevalences of gastroesophageal reflux disease (GERD) and dyspepsia using Rome III criteria in Asian countries.
methodsA population-based, cross-sectional study was conducted by telephone interviews of 5,000 Koreans between the ages of 20-69 years. Gastrointestinal symptoms were assessed by a translated Korean version of Rome III criteria. Uninvestigated dyspepsia (UID) was defined by symptom criteria of Rome III. GERD was defined by troublesome heartburn and/or acid regurgitation occurring at least once a week. The EQ5D assessment tool was used for the evaluation of quality of life.
resultsThe prevalences of UID, postprandial distress syndrome (PDS), and epigastric pain syndrome (EPS) were 7.7, 5.6, and 4.2 %, respectively. Overlap between PDS and EPS was found in 27.1 % (104/384) of subjects with UID. There were no significant differences in demographic variables between patients with PDS and EPS. The prevalence of GERD was 7.1 %. Overlap between GERD and UID was found in 50.0 % of GERD patients. The EQ5D index of patients without either UID or GERD was 0.92 ± 0.07, and those of patients with only UID, with only GERD, and with both UID and GERD were 0.88 ± 0.09, 0.88 ± 0.11, and 0.84 ± 0.15, respectively.
conclusionsGERD and UID based on Rome III criteria were prevalent and significantly affected the quality of life in Korea. In Korean patients with UID, there was considerable overlap and there were no significant differences in demographic variables between PDS and EPS.
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