ArticlePloS one2014
Mechanisms of tolerance and high degradation capacity of the herbicide mesotrione by Escherichia coli strain DH5-α.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21 citing papers in PubMed, 52 citations in OpenAlex.
- Biodegradation of chlorpyrifos by the newly isolated Escherichia fergusonii and Clostridium bifermentans: Identification and growth optimization for bioremediation.Scientific reports · 2026Article
- Efficiency of Imazapic Degradation: an Assessment of LacMeta Treatments Utilizing Whole Cell.Current microbiology · 2026Article
- Microbial mechanisms as tools for monitoring and treating emerging contaminants in urban pollution: an overview.Archives of microbiology · 2026Review
- Evolution and Future Directions in Herbicide-Resistant Crop Development and Weed Management.Rice (New York, N.Y.) · 2025Review
- Description of Paenibacillus jiagnxiensis sp. nov., a mesotrione-degrading bacterium isolated from farmland and cloning of a novel mesotrione nitroreductase gene.Antonie van Leeuwenhoek · 2025Article
- Tolerance to Herbicides and Resistance to Antibacterial Drugs of Bacterial Isolates From the Guarani Aquifer System (Brazil).Environmental microbiology · 2025Article
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- Molecular Research of Lipid Peroxidation and Antioxidant Enzyme Activity ofInternational journal of molecular sciences · 2022Article
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- Photosynthetic and physiological responses to acetochlor in paired near-isogenic lines of waxy maize (Zea mays L.).Environmental science and pollution research international · 2021Article
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- Herbicides Tolerance in aFrontiers in microbiology · 2021Article
- Review
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- Evidence for photolytic and microbial degradation processes in the dissipation of leptospermone, a natural β-triketone herbicide.Environmental science and pollution research international · 2018Article
- Bacillus megaterium strains derived from water and soil exhibit differential responses to the herbicide mesotrione.PloS one · 2018Article
- Quantification of the fate of mesotrione applied alone or in a herbicide mixture in two Brazilian arable soils.Environmental science and pollution research international · 2017Article
- GST activity and membrane lipid saturation prevents mesotrione-induced cellular damage in Pantoea ananatis.AMB Express · 2016Article
- Isolation and characterization of Bradyrhizobium sp. SR1 degrading two β-triketone herbicides.Environmental science and pollution research international · 2016Article
- Ecotoxicological Impact of the Bioherbicide Leptospermone on the Microbial Community of Two Arable Soils.Frontiers in microbiology · 2016Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The intensive use of agrochemicals has played an important role in increasing agricultural production. One of the impacts of agrochemical use has been changes in population structure of soil microbiota. The aim of this work was to analyze the adaptive strategies that bacteria use to overcome oxidative stress caused by mesotrione, which inhibits 4-hydroxyphenylpyruvate dioxygenase. We also examined antioxidative stress systems, saturation changes of lipid membranes, and the capacity of bacteria to degrade mesotrione. Escherichia coli DH5-á was chosen as a non-environmental strain, which is already a model bacterium for studying metabolism and adaptation. The results showed that this bacterium was able to tolerate high doses of the herbicide (10× field rate), and completely degraded mesotrione after 3 h of exposure, as determined by a High Performance Liquid Chromatography. Growth rates in the presence of mesotrione were lower than in the control, prior to the period of degradation, showing toxic effects of this herbicide on bacterial cells. Changes in the saturation of the membrane lipids reduced the damage caused by reactive oxygen species and possibly hindered the entry of xenobiotics in the cell, while activating glutathione-S-transferase enzyme in the antioxidant system and in the metabolizing process of the herbicide. Considering that E. coli DH5-α is a non-environmental strain and it had no previous contact with mesotrione, the defense system found in this strain could be considered non-specific. This bacterium system response may be a general adaptation mechanism by which bacterial strains resist to damage from the presence of herbicides in agricultural soils.
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