Evidence map›Paper›PMID 24923990›Full record

ReviewWiley interdisciplinary reviews. RNA

Emerging mechanisms of mRNP remodeling regulation.

Chyi-Ying A Chen, Ann-Bin Shyu

Abstract readReview
In one paragraph

Review in Wiley interdisciplinary reviews. RNA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
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  8. A brave new world of RNA-binding proteins.Nature reviews. Molecular cell biology · 2018
    Review
  9. Article
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  11. Article
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Chyi-Ying A ChenDepartment of Biochemistry and Molecular Biology, The University of Texas, Medical School at Houston, Houston, TX, USA.
Ann-Bin Shyu
The University of Texas Health Science Center at Houston · US

Funding

Messenger RNA Turnover in Mammalian CellsR01GM046454 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI SHYU, ANN-BIN · 1991 to 2016
$7.1M
NIGMS NIH HHS R01 GM046454
6 · The paper itself

Abstract

The assembly and remodeling of the components of messenger ribonucleoprotein particles (mRNPs) are important in determining the fate of a messenger RNA (mRNA). A combination of biochemical and cell biology research, recently complemented by genome-wide high-throughput approaches, has led to significant progress on understanding the formation, dynamics, and function of mRNPs. These studies also advanced the challenging process of identifying the evolving constituents of individual mRNPs at various stages during an mRNA's lifetime. While research on mRNP remodeling in general has been gaining momentum, there has been relatively little attention paid to the regulatory aspect of mRNP remodeling. Here, we discuss the results of some new studies and potential mechanisms for regulation of mRNP remodeling.

Indexed as

Cell NucleusHumansIntrinsically Disordered ProteinsPhosphorylationPoly(A)-Binding ProteinsProtein BiosynthesisRibonucleoproteinsRNA, MessengerUbiquitinationIntrinsically Disordered Proteinsmessenger ribonucleoproteinPoly(A)-Binding ProteinsRibonucleoproteinsRNA, Messenger

Identifiers

PMID24923990
PMCPMC4323169
OpenAlexW2104866072

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.