ArticleAsian journal of andrology
Bringing epigenetics into the diagnostics of the andrology laboratory: challenges and perspectives.
Article in Asian journal of andrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Pooled it
- Sperm Imprinted Gene Methylation and DNA Fragmentation in ICSI Outcomes: A Pilot Study.Epigenomes · 2026Article
- Article
- Sperm miR-34c-5p Transcript Content and Its Association with Sperm Parameters in Unexplained Infertile Men.Reproductive sciences (Thousand Oaks, Calif.) · 2022Article
- Epigenetics of Male Infertility: The Role of DNA Methylation.Frontiers in cell and developmental biology · 2021Review
- Profiling the DNA methylation patterns of imprinted genes in abnormal semen samples by next-generation bisulfite sequencing.Journal of assisted reproduction and genetics · 2020Article
- Environmental Impact on Male (In)Fertility via Epigenetic Route.Journal of clinical medicine · 2020Review
- The sperm epigenome does not display recurrent epimutations in patients with severely impaired spermatogenesis.Clinical epigenetics · 2020Article
- Sperm DNA Integrity and Male Fertility in Farm Animals: A Review.Frontiers in veterinary science · 2020Review
- Do paternal semen parameters influence the birth weight or BMI of the offspring? A study from the Utah Population Database.Journal of assisted reproduction and genetics · 2018Article
- Guidance and Self-Sorting of Active Swimmers: 3D Periodic Arrays Increase Persistence Length of Human Sperm Selecting for the Fittest.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2018Article
- Imprinting alterations in sperm may not significantly influence ART outcomes and imprinting patterns in the cord blood of offspring.PloS one · 2017Article
- Epigenetics: A key paradigm in reproductive health.Clinical and experimental reproductive medicine · 2016Review
- The role of epigenetics in idiopathic male infertility.Journal of assisted reproduction and genetics · 2016Review
- [Social freezing - the male perspective].Der Urologe. Ausg. A · 2016Review
- Environmental Impact on DNA Methylation in the Germline: State of the Art and Gaps of Knowledge.BioMed research international · 2015Review
- Limitations of semen analysis as a test of male fertility and anticipated needs from newer tests.Fertility and sterility · 2014Review
- Prospects for clinically relevant epigenetic tests in the andrology laboratory.Asian journal of andrologyArticle
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent studies have shown significant associations of aberrant DNA methylation in spermatozoa with idiopathic male infertility, increased frequency of spontaneous abortions and imprinting disorders. Thus, the analysis of DNA methylation of specific genes in spermatozoa has the potential to become a new valuable diagnostic marker in clinical andrology. This perspective article discusses the current state and value of DNA methylation analysis in the diagnostic setup of infertile men and outlines challenges and perspectives. It highlights the potential of DNA methylation in andrological diagnostics and its putative benefit in the examination of hitherto idiopathic infertile patients is described.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.