ArticleBMC medical ethics2014
Child's assent in research: age threshold or personalisation?
Article in BMC medical ethics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk and surrogate benefit for pediatric Phase I trials in oncology: A systematic review with meta-analysis.PLoS medicine · 2018Pooled it
- Children's participation in assent to paediatric oncology research: experiences of children, siblings and parents.Trials · 2026Article
- Risk and benefit for targeted therapy agents in paediatric phase I trials in oncology: a systematic review and meta-analysis protocol.BMJ open · 2026Article
- Why children's research assent matters: Exploring three dimensions of autonomy.Nursing ethics · 2026Article
- Ethical and Legal Aspects of Informed Consent and Assent in Paediatric Dentistry: A Cross-Sectional Study.Children (Basel, Switzerland) · 2025Article
- Analysis of pediatric assent information in early-phase cancer clinical trials through a children's research advisory group.Frontiers in psychology · 2025Article
- Evaluating the Performance of FlukeCatcher at Detecting Urogenital Schistosomiasis.Diagnostics (Basel, Switzerland) · 2024Article
- Pre- and post-implementation protocol for non-operative management of grade III-V splenic injuries: An observational study.Heliyon · 2024Article
- Parents' perceptions of parental consent procedures for social science research in the school context.International journal of social research methodology · 2024Article
- Assent, parental consent and reconsent for health research in Africa: thematic analysis of national guidelines and lessons from the SickleInAfrica registry.BMC medical ethics · 2022Article
- What information and the extent of information to be provided in an informed assent/consent form of pediatric drug trials.BMC medical ethics · 2022Article
- Informed Consent in Clinical Studies Involving Human Participants: Ethical Insights of Medical Researchers in Germany and Poland.Frontiers in medicine · 2022Article
- Children's Understanding of Informed Assents in Research Studies.Healthcare (Basel, Switzerland) · 2021Article
- Adolescent Assent and Reconsent for Biobanking: Recent Developments and Emerging Ethical Issues.Frontiers in medicine · 2021Review
- Assent and consent in adolescent research: teachers' perspectives from a developing country.Heliyon · 2020Article
- PREVALENCE AND CLINICAL FORMS OF MALARIA AMONG FEBRILE HIV-INFECTED CHILDREN SEEN AT USMANU DANFODIYO UNIVERSITY TEACHING HOSPITAL, SOKOTO, NIGERIA.African journal of infectious diseases · 2020Article
- How should assent to research be sought in low income settings? Perspectives from parents and children in Southern Malawi.BMC medical ethics · 2019Article
- Unmet Needs in Children With Attention Deficit Hyperactivity Disorder-Can Transcranial Direct Current Stimulation Fill the Gap? Promises and Ethical Challenges.Frontiers in psychiatry · 2019Article
- Standardized approaches for clinical sampling and endpoint ascertainment in tuberculous meningitis studies.Wellcome open research · 2019Article
- Personalized assent for pediatric biobanks.BMC medical ethics · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAssent is an important ethical and legal requirement of paediatric research. Unfortunately, there are significant differences between the guidelines on the details of assent. DISCUSSION: What often remains unclear is the scope of the assent, the procedure for acquiring it, and the way in which children's capacity to assent is determined. There is a general growing tendency that suggests that the process of assent should be personalised, that is, tailored to a particular child. This article supports the idea of personalisation. However, we also propose placing limits on personalisation by introducing a suggested requirement of assent starting at a school-age threshold. In some situations RECs/IRBs and researchers could reduce the suggested threshold. SUMMARY: A recommended age threshold is likely to serve the interests of children better than ambiguous and flexible criteria for personalised age determination.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.