SynthesisAmerican journal of public health2014
Meta-analysis of all-cause mortality according to serum 25-hydroxyvitamin D.
Synthesis in American journal of public health, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers, 10 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
99 citing papers in PubMed, 10 syntheses or guidelines pooled it.
- Pooled it
- Severe Vitamin D Deficiency-A Possible Cause of Resistance to Treatment in Psychiatric Pathology.Medicina (Kaunas, Lithuania) · 2023Pooled it
- Pooled it
- Vitamin D and Multiple Health Outcomes: An Umbrella Review of Observational Studies, Randomized Controlled Trials, and Mendelian Randomization Studies.Advances in nutrition (Bethesda, Md.) · 2022Pooled it
- Effects of vitamin D supplementation on blood markers in ulcerative colitis patients: a systematic review and meta-analysis.European journal of nutrition · 2022Pooled it
- The Influence of Vitamin D Intake and Status on Mental Health in Children: A Systematic Review.Nutrients · 2021Pooled it
- Vitamin D Status and Mortality: A Systematic Review of Observational Studies.International journal of environmental research and public health · 2019Pooled it
- Guideline
- 25-Hydroxyvitamin D Status and Risk for Colorectal Cancer and Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Epidemiological Studies.International journal of environmental research and public health · 2017Pooled it
- Pooled it
- Vitamin D deficiency is highly prevalent in malnourished inpatients and associated with higher mortality: A prospective cohort study.Medicine · 2019Trial
- Open-label study of treatment with alendronate sodium plus vitamin D in men and women with osteoporosis in Thailand.BMC musculoskeletal disorders · 2018Trial
- Evolution of Serum 25OHD in Response to Vitamin DJournal of the American College of Nutrition · 2018Trial
- Optimum dose of vitamin D for disease prevention in older people: BEST-D trial of vitamin D in primary care.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017Trial
- Maternal Versus Infant Vitamin D Supplementation During Lactation: A Randomized Controlled Trial.Pediatrics · 2015Trial
- Biological Aging Mediates the Associations Between Multiple Serum Micronutrients and All-Cause Mortality Among U.S. Adults.Biological trace element research · 2026Article
- Vitamin D in Type 2 Diabetes Mellitus According to Diabetic Kidney Disease Stage: What Is the Target in Clinical Practice?Nutrients · 2026Article
- 25-Hydroxyvitamin D levels are associated with mortality and cardiovascular events in systemic lupus erythematosus.Annals of the rheumatic diseases · 2026Article
- Article
- Vitamin D signaling in thymic development and longevity.Frontiers in nutrition · 2026Article
39 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We examined the relationship between serum 25-hydroxyvitamin D (25[OH]D) and all-cause mortality. We searched biomedical databases for articles that assessed 2 or more categories of 25(OH)D from January 1, 1966, to January 15, 2013. We identified 32 studies and pooled the data. The hazard ratio for all-cause mortality comparing the lowest (0-9 nanograms per milliliter [ng/mL]) to the highest (> 30 ng/mL) category of 25(OH)D was 1.9 (95% confidence interval = 1.6, 2.2; P < .001). Serum 25(OH)D concentrations less than or equal to 30 ng/mL were associated with higher all-cause mortality than concentrations greater than 30 ng/mL (P < .01). Our findings agree with a National Academy of Sciences report, except the cutoff point for all-cause mortality reduction in this analysis was greater than 30 ng/mL rather than greater than 20 ng/mL.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.