ArticlePhotoacoustics2014
Nonlinear photoacoustic signal amplification from single targets in absorption background.
Article in Photoacoustics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Photoacoustic imaging for cutaneous melanoma assessment: a comprehensive review.Journal of biomedical optics · 2024Pooled it
- Nonlinearity of optoacoustic signals and a new contrast mechanism for imaging.Light, science & applications · 2025Article
- Supramolecular dye nanoassemblies for advanced diagnostics and therapies.Bioengineering & translational medicine · 2024Review
- High-Throughput Single-Cell Analysis of Nanoparticle-Cell Interactions.Trends in analytical chemistry : TRAC · 2023Article
- Morphology-dependent resonance enhanced nonlinear photoacoustic effect in nanoparticle suspension: a temporal-spatial model.Biomedical optics express · 2021Article
- Optical dosimeter for selective retinal therapy based on multi-port fiber-optic interferometry.Biomedical optics express · 2021Article
- Nonlinear mechanisms in photoacoustics-Powerful tools in photoacoustic imaging.Photoacoustics · 2021Review
- Listening to tissues with new light: recent technological advances in photoacoustic imaging.Journal of optics (2010) · 2019Article
- In vivo liquid biopsy using Cytophone platform for photoacoustic detection of circulating tumor cells in patients with melanoma.Science translational medicine · 2019Article
- Molecular Photoacoustic Contrast Agents: Design Principles & Applications.Photochemistry and photobiology · 2018Review
- Visualization of murine lymph vessels using photoacoustic imaging with contrast agents.Photoacoustics · 2018Article
- In vivo noninvasive analysis of graphene nanomaterial pharmacokinetics using photoacoustic flow cytometry.Journal of applied toxicology : JAT · 2017Article
- An analytical study of photoacoustic and thermoacoustic generation efficiency towards contrast agent and film design optimization.Photoacoustics · 2017Article
- Spaser as a biological probe.Nature communications · 2017Article
- Listening to membrane potential: photoacoustic voltage-sensitive dye recording.Journal of biomedical optics · 2017Article
- Preclinical photoacoustic models: application for ultrasensitive single cell malaria diagnosis in large vein and artery.Biomedical optics express · 2016Article
- Optical clearing of skin enhanced with hyaluronic acid for increased contrast of optoacoustic imaging.Journal of biomedical optics · 2016Article
- Article
- Photoacoustic Flow Cytometry for Single Sickle Cell DetectionAnalytical cellular pathology (Amsterdam) · 2016Article
- Arterial Blood, Rather Than Venous Blood, is a Better Source for Circulating Melanoma Cells.EBioMedicine · 2015Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Photoacoustic (PA) detection of single absorbing targets such as nanoparticles or cells can be limited by absorption background. We show here that this problem can be overcome by using the nonlinear photoacoustics based on the differences in PA signal dependences on the laser energy from targets and background. Among different nonlinear phenomena, we focused on laser generation of nanobubbles as more efficient PA signal amplifiers from strongly absorbing, highly localized targets in the presence of spatially homogenous absorption background generating linear signals only. This approach was demonstrated by using nonlinear PA flow cytometry platform for label-free detection of circulating melanoma cells in blood background
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.