Evidence map›Paper›PMID 24921061›Full record

ArticleAdolescent psychiatry (Hilversum, Netherlands)2013

Novel Drugs of Abuse: A Snapshot of an Evolving Marketplace.

Ryan Vandrey, Matthew W Johnson, Patrick S Johnson, Miral A Khalil

Abstract read
In one paragraph

Article in Adolescent psychiatry (Hilversum, Netherlands), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Psychoactive Substances Bill and Act of New Zealand: A Chance to Engage Undergraduate Scientists with Society using a Transfer Learning Paradigm.Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience · 2015
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ryan VandreyJohns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Matthew W JohnsonJohns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Patrick S JohnsonJohns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Miral A KhalilJohns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Funding

HUMAN BEHAVIORAL PHARMACOLOGY OF SUBSTANCE ABUSET32DA007209 · NIDA · JOHNS HOPKINS UNIVERSITY · PI Eric C. Strain, Elise M Weerts · 1985 to 2026
$12.9M
Human Clinical Pharmacology of Emerging Drugs of Abuse (Club Drugs)R01DA003889 · NIDA · JOHNS HOPKINS UNIVERSITY · PI GRIFFITHS, ROLAND R · 1985 to 2017
$7.6M
Role of Sleep in the Treatment of Cannabis DependenceU01DA031784 · NIDA · JOHNS HOPKINS UNIVERSITY · PI VANDREY, RYAN G · 2012 to 2016
$3.2M
Efficacy and Safety of Dronabinol (Oral THC) for Treating Cannabis DependenceR01DA025044 · NIDA · JOHNS HOPKINS UNIVERSITY · PI VANDREY, RYAN G · 2009 to 2012
$2.0M
Role of delay discounting in driving HIV sexual risk behavior in cocaine abuseR01DA032363 · NIDA · JOHNS HOPKINS UNIVERSITY · PI JOHNSON, MATTHEW WAYNE · 2012 to 2014
$959k
HIV Sexual Risk Behavior: Methamphetamine and Delay Discounting of Sexual RewardsR21DA032717 · NIDA · JOHNS HOPKINS UNIVERSITY · PI JOHNSON, MATTHEW WAYNE · 2012 to 2013
$409k
NIDA NIH HHS R01 DA003889NIDA NIH HHS R01 DA025044NIDA NIH HHS R01 DA032363NIDA NIH HHS R21 DA032717NIDA NIH HHS T32 DA007209NIDA NIH HHS U01 DA031784
6 · The paper itself

Abstract

BACKGROUND &

objectivesOver the past decade, non-medical use of novel drugs has proliferated worldwide. In most cases these are synthetic drugs first synthesized in academic or pharmaceutical laboratories for research or drug development purposes, but also include naturally occurring substances that do not fit the typical pharmacological or behavioral profile of traditional illicit substances. Perhaps most unique to this generation of new drugs is that they are being sold over the counter and on the Internet as "legal highs" or substitutes for traditional illicit drugs such as cannabis, cocaine, amphetamines, MDMA, and LSD. The purpose of this review is to provide an overview of novel drugs in current use, including the epidemiology of use and toxicologic and pharmacological properties, and to offer some guidelines to clinicians who see patients experiencing adverse effects from these drugs.

methodWe review the known scientific literature on recently introduced synthetic drug types, synthetic cannabinoids and synthetic cathinones, and the hallucinogen

resultsThese substances comprise part of a rapidly evolving and controversial drug market that has challenged definitions of what is legal and illegal, has benefitted from open commercial sales without regulatory oversight, and is noteworthy for the pace at which new substances are introduced.

conclusionsThis emerging trend in substance use presents significant and unique public health and criminal justice challenges. At this time, these substances are not detected in routine drug screens and substance-specific treatment for cases of use-related toxicity are not available. Clinicians are encouraged to learn characteristic signs associated with misuse of novel drugs to recognize cases in their practice, and are recommended to use a symptom-specific approach for treatment in each case.

Indexed as

Bath SaltscannabinoidscathinonesSalvia divinorumSalvonirin ASpiceSynthetic drugs

Identifiers

PMID24921061
PMCPMC4049139

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.