ArticleJournal of vascular and interventional neurology2014
Vitamin D deficiency and osteoporosis in stroke survivors: an analysis of National Health and Nutritional Examination Survey (NHANES).
Article in Journal of vascular and interventional neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
8 citing papers in PubMed, 18 citations in OpenAlex.
- Cross-Sectional Study of Bone Mineral Density in Chronic Stroke According to Walking Speed.Journal of clinical medicine · 2025Article
- The pathogenesis of post-stroke osteoporosis and the role oxidative stress plays in its development.Frontiers in medicine · 2023Review
- Vitamin D3 and Ischemic Stroke: A Narrative Review.Antioxidants (Basel, Switzerland) · 2022Review
- Change in Bone Mineral Density in Stroke Patients with Osteoporosis or Osteopenia.International journal of environmental research and public health · 2022Article
- Effect of vitamin D supplementation on lower extremity motor function and ambulation in stroke patientsTurkish journal of medical sciences · 2021Article
- Development of a sensitive HPLC-MS/MS method for 25-hydroxyvitamin DJournal of clinical laboratory analysis · 2020Article
- The Importance of Assessing Nutritional Status to Ensure Optimal Recovery during the Chronic Phase of Stroke.Stroke research and treatment · 2018Review
- Glycated hemoglobin A1C and vitamin D and their association with diabetic retinopathy severity.Nutrition & diabetes · 2017Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
background and purposeAn inverse association between 25-hydroxyvitamin D (25[OH]D) levels and stroke was emphasized in recent studies. Our objective was to determine the rate of Vitamin D deficiency and risk of associated osteoporosis among stroke survivors in a nationally representative population.
methodsParticipants from the National Health and Nutritional Examination Survey (NHANES) from 2001 to 2006 were included. Stroke survivors were then divided into two groups depending on serum 25(OH)D levels: <30 ng/dl as Vitamin D deficiency and ≥30 ng/dl as normal. Comparisons of demographics and risk factors between two groups were performed using SAS software. Multivariate analysis was performed to determine the association between Vitamin D deficiency and osteopororis in stroke survivors after adjusting for potential confounding factors.
resultsThere were 415 (4.0%) stroke survivors among 10,255 participants in NHANES. The mean age (±SD) of stroke survivors was 67.6 (±17.3) years and 211 (50.8%) were men. Mean 25(OH)D concentrations were not significantly different in patients with stroke (20.3 versus 21.8 ng/ml, p = 0.65) although the rate of osteoporosis was significantly higher among stroke survivors (17.9% versus 6.9%, p < 0.0001). Out of 415 stroke patients, Vitamin D deficiency was seen in 71.0% of patients. The rates of osteoporosis were similar between patients with or without Vitamin D deficiency. After adjusting for potential confounders, there was no association between Vitamin D deficiency and osteoporosis.
conclusionsVitamin D deficiency and osteoporosis are highly prevalent among stroke survivors; however, there does not appear to be a relationship between the two entities.
Indexed as
Identifiers
24920985PMC4051901W1580567520What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.