Evidence map›Paper›PMID 24920445›Full record

ArticlePlant physiology2014

Functional and Evolutionary Analysis of the CASPARIAN STRIP MEMBRANE DOMAIN PROTEIN Family.

Daniele Roppolo, Brigitte Boeckmann, Alexandre Pfister, Emmanuel Boutet, Maria C Rubio, Valérie Dénervaud-Tendon, Joop E M Vermeer, Jacqueline Gheyselinck, Ioannis Xenarios, Niko Geldner

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Article in Plant physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Daniele RoppoloDepartment of Plant Molecular Biology, University of Lausanne, Quartier Sorge, Lausanne 1015, Switzerland (D.R., A.P., M.C.R., V.D.-T., J.E.M.V., N.G.);Swiss Institute of Bioinformatics, Centre Médical Universitaire, 1211 Geneva 4, Switzerland (B.B., E.B., I.X.);Departamento de Nutrición Vegetal, Estación Experimental de Aula Dei, Consejo Superior de Investigaciones Científicas, 50080 Zaragoza, Spain (M.C.R.);Vital-IT Group and University of Lausanne, Quartier Sorge, Bâtiment Génopode, Lausanne 1015, Switzerland (I.X.); andInstitute of Plant Sciences, University of Bern, 3013 Bern, Switzerland (D.R., J.G.) daniele.roppolo@ips.unibe.ch.
Brigitte BoeckmannDepartment of Plant Molecular Biology, University of Lausanne, Quartier Sorge, Lausanne 1015, Switzerland (D.R., A.P., M.C.R., V.D.-T., J.E.M.V., N.G.);Swiss Institute of Bioinformatics, Centre Médical Universitaire, 1211 Geneva 4, Switzerland (B.B., E.B., I.X.);Departamento de Nutrición Vegetal, Estación Experimental de Aula Dei, Consejo Superior de Investigaciones Científicas, 50080 Zaragoza, Spain (M.C.R.);Vital-IT Group and University of Lausanne, Quartier Sorge, Bâtiment Génopode, Lausanne 1015, Switzerland (I.X.); andInstitute of Plant Sciences, University of Bern, 3013 Bern, Switzerland (D.R., J.G.).
Alexandre PfisterDepartment of Plant Molecular Biology, University of Lausanne, Quartier Sorge, Lausanne 1015, Switzerland (D.R., A.P., M.C.R., V.D.-T., J.E.M.V., N.G.);Swiss Institute of Bioinformatics, Centre Médical Universitaire, 1211 Geneva 4, Switzerland (B.B., E.B., I.X.);Departamento de Nutrición Vegetal, Estación Experimental de Aula Dei, Consejo Superior de Investigaciones Científicas, 50080 Zaragoza, Spain (M.C.R.);Vital-IT Group and University of Lausanne, Quartier Sorge, Bâtiment Génopode, Lausanne 1015, Switzerland (I.X.); andInstitute of Plant Sciences, University of Bern, 3013 Bern, Switzerland (D.R., J.G.).
Emmanuel BoutetDepartment of Plant Molecular Biology, University of Lausanne, Quartier Sorge, Lausanne 1015, Switzerland (D.R., A.P., M.C.R., V.D.-T., J.E.M.V., N.G.);Swiss Institute of Bioinformatics, Centre Médical Universitaire, 1211 Geneva 4, Switzerland (B.B., E.B., I.X.);Departamento de Nutrición Vegetal, Estación Experimental de Aula Dei, Consejo Superior de Investigaciones Científicas, 50080 Zaragoza, Spain (M.C.R.);Vital-IT Group and University of Lausanne, Quartier Sorge, Bâtiment Génopode, Lausanne 1015, Switzerland (I.X.); andInstitute of Plant Sciences, University of Bern, 3013 Bern, Switzerland (D.R., J.G.).
Maria C RubioDepartment of Plant Molecular Biology, University of Lausanne, Quartier Sorge, Lausanne 1015, Switzerland (D.R., A.P., M.C.R., V.D.-T., J.E.M.V., N.G.);Swiss Institute of Bioinformatics, Centre Médical Universitaire, 1211 Geneva 4, Switzerland (B.B., E.B., I.X.);Departamento de Nutrición Vegetal, Estación Experimental de Aula Dei, Consejo Superior de Investigaciones Científicas, 50080 Zaragoza, Spain (M.C.R.);Vital-IT Group and University of Lausanne, Quartier Sorge, Bâtiment Génopode, Lausanne 1015, Switzerland (I.X.); andInstitute of Plant Sciences, University of Bern, 3013 Bern, Switzerland (D.R., J.G.).
Valérie Dénervaud-TendonDepartment of Plant Molecular Biology, University of Lausanne, Quartier Sorge, Lausanne 1015, Switzerland (D.R., A.P., M.C.R., V.D.-T., J.E.M.V., N.G.);Swiss Institute of Bioinformatics, Centre Médical Universitaire, 1211 Geneva 4, Switzerland (B.B., E.B., I.X.);Departamento de Nutrición Vegetal, Estación Experimental de Aula Dei, Consejo Superior de Investigaciones Científicas, 50080 Zaragoza, Spain (M.C.R.);Vital-IT Group and University of Lausanne, Quartier Sorge, Bâtiment Génopode, Lausanne 1015, Switzerland (I.X.); andInstitute of Plant Sciences, University of Bern, 3013 Bern, Switzerland (D.R., J.G.).
Joop E M VermeerDepartment of Plant Molecular Biology, University of Lausanne, Quartier Sorge, Lausanne 1015, Switzerland (D.R., A.P., M.C.R., V.D.-T., J.E.M.V., N.G.);Swiss Institute of Bioinformatics, Centre Médical Universitaire, 1211 Geneva 4, Switzerland (B.B., E.B., I.X.);Departamento de Nutrición Vegetal, Estación Experimental de Aula Dei, Consejo Superior de Investigaciones Científicas, 50080 Zaragoza, Spain (M.C.R.);Vital-IT Group and University of Lausanne, Quartier Sorge, Bâtiment Génopode, Lausanne 1015, Switzerland (I.X.); andInstitute of Plant Sciences, University of Bern, 3013 Bern, Switzerland (D.R., J.G.).
Jacqueline GheyselinckDepartment of Plant Molecular Biology, University of Lausanne, Quartier Sorge, Lausanne 1015, Switzerland (D.R., A.P., M.C.R., V.D.-T., J.E.M.V., N.G.);Swiss Institute of Bioinformatics, Centre Médical Universitaire, 1211 Geneva 4, Switzerland (B.B., E.B., I.X.);Departamento de Nutrición Vegetal, Estación Experimental de Aula Dei, Consejo Superior de Investigaciones Científicas, 50080 Zaragoza, Spain (M.C.R.);Vital-IT Group and University of Lausanne, Quartier Sorge, Bâtiment Génopode, Lausanne 1015, Switzerland (I.X.); andInstitute of Plant Sciences, University of Bern, 3013 Bern, Switzerland (D.R., J.G.).
Ioannis XenariosDepartment of Plant Molecular Biology, University of Lausanne, Quartier Sorge, Lausanne 1015, Switzerland (D.R., A.P., M.C.R., V.D.-T., J.E.M.V., N.G.);Swiss Institute of Bioinformatics, Centre Médical Universitaire, 1211 Geneva 4, Switzerland (B.B., E.B., I.X.);Departamento de Nutrición Vegetal, Estación Experimental de Aula Dei, Consejo Superior de Investigaciones Científicas, 50080 Zaragoza, Spain (M.C.R.);Vital-IT Group and University of Lausanne, Quartier Sorge, Bâtiment Génopode, Lausanne 1015, Switzerland (I.X.); andInstitute of Plant Sciences, University of Bern, 3013 Bern, Switzerland (D.R., J.G.).
Niko GeldnerDepartment of Plant Molecular Biology, University of Lausanne, Quartier Sorge, Lausanne 1015, Switzerland (D.R., A.P., M.C.R., V.D.-T., J.E.M.V., N.G.);Swiss Institute of Bioinformatics, Centre Médical Universitaire, 1211 Geneva 4, Switzerland (B.B., E.B., I.X.);Departamento de Nutrición Vegetal, Estación Experimental de Aula Dei, Consejo Superior de Investigaciones Científicas, 50080 Zaragoza, Spain (M.C.R.);Vital-IT Group and University of Lausanne, Quartier Sorge, Bâtiment Génopode, Lausanne 1015, Switzerland (I.X.); andInstitute of Plant Sciences, University of Bern, 3013 Bern, Switzerland (D.R., J.G.).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CASPARIAN STRIP MEMBRANE DOMAIN PROTEINS (CASPs) are four-membrane-span proteins that mediate the deposition of Casparian strips in the endodermis by recruiting the lignin polymerization machinery. CASPs show high stability in their membrane domain, which presents all the hallmarks of a membrane scaffold. Here, we characterized the large family of CASP-like (CASPL) proteins. CASPLs were found in all major divisions of land plants as well as in green algae; homologs outside of the plant kingdom were identified as members of the MARVEL protein family. When ectopically expressed in the endodermis, most CASPLs were able to integrate the CASP membrane domain, which suggests that CASPLs share with CASPs the propensity to form transmembrane scaffolds. Extracellular loops are not necessary for generating the scaffold, since CASP1 was still able to localize correctly when either one of the extracellular loops was deleted. The CASP first extracellular loop was found conserved in euphyllophytes but absent in plants lacking Casparian strips, an observation that may contribute to the study of Casparian strip and root evolution. In Arabidopsis (Arabidopsis thaliana), CASPL showed specific expression in a variety of cell types, such as trichomes, abscission zone cells, peripheral root cap cells, and xylem pole pericycle cells.

Identifiers

PMID24920445
PMCPMC4119050

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