Evidence map›Paper›PMID 24920288›Full record

ArticleFEMS yeast research2014

L-Dihydroxyphenylalanine induces melanin production by members of the genus Trichosporon.

Maria Helena Galdino Figueiredo-Carvalho, Fábio B dos Santos, Joshua D Nosanchuk, Rosely M Zancope-Oliveira, Rodrigo Almeida-Paes

Open access · bronzeAbstract read
In one paragraph

Article in FEMS yeast research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Future microbiology · 2025
    Review
  2. Two Cases of Fungal Melanonychia.Acta dermato-venereologica · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Beyond Melanin: Proteomics Reveals Virulence-Related Proteins inJournal of fungi (Basel, Switzerland) · 2020
    Article
  8. Article
  9. Article
  10. The Cell Biology of theFrontiers in cellular and infection microbiology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Maria Helena Galdino Figueiredo-CarvalhoLaboratório de Micologia, Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz, Manguinhos, Rio de Janeiro, Brazil.
Fábio B dos Santos
Joshua D Nosanchuk
Rosely M Zancope-Oliveira
Rodrigo Almeida-Paes
Fundação Oswaldo Cruz · BRAlbert Einstein College of Medicine · US

Funding

Biology of Fungal MelaninR01AI052733 · NIAID · YESHIVA UNIVERSITY · PI CASADEVALL, ARTURO · 2003 to 2019
$6.6M
NIAID NIH HHS AI52733NIAID NIH HHS R01 AI052733
6 · The paper itself

Abstract

Melanization of members of the genus Trichosporon is poorly described. In this study, six strains, including two clinical isolates, from four different species (Trichosporon asahii, T. asteroides, T. inkin, and T. mucoides) were grown in culture media with or without L-dihydroxyphenylalanine (L-DOPA). Each strain produced a brownish pigment compatible with melanin when cultured in presence of L-DOPA, suggesting that these species are able to produce eumelanin. L-tyrosine was not able to elicit any type of pigment production on cultures. As eumelanin is produced by several fungi during parasitism, this pigment may contribute to Trichosporon virulence.

Indexed as

Culture MediaDihydroxyphenylalanineHumansMelaninsPhenotypeTrichosporonCulture MediaDihydroxyphenylalanineMelaninsl-DOPAmelaninTrichosporon

Identifiers

PMID24920288
PMCPMC4160383
OpenAlexW2144188047

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.