ArticleJournal of endocrinological investigation2014
Isolated hyperthyrotropinemia in childhood obesity and its relation with metabolic parameters.
Article in Journal of endocrinological investigation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 17 citations in OpenAlex.
- Association between thyrotropin levels and insulin sensitivity in euthyroid obese adolescents.Thyroid : official journal of the American Thyroid Association · 2015Trial
- Insulin resistance, leptin and adiponectin in lean and hypothyroid children and adolescents with obesity.BMC pediatrics · 2022Article
- The Frequency of Subclinical Hypothyroidism in Obese Children and Adolescents and Its Relationship with Metabolic Parameters and Atherogenic Index.Turkish archives of pediatrics · 2022Article
- Isolated Hyperthyrotropinemia Adversely Influences Lipid Metabolism in Children and Adolescents with Obesity.Turkish archives of pediatrics · 2022Article
- Is Waist-height Ratio Associated with Thyroid Antibody Levels in Children with Obesity?Journal of clinical research in pediatric endocrinology · 2021Article
- Influence of subclinical hypothyroidism on metabolic parameters in obese children and adolescents.Clinical and experimental pediatrics · 2020Article
- Thyroid Function in Korean Adolescents with Obesity: Results from the Korea National Health and Nutrition Examination Survey VI (2013-2015).International journal of endocrinology · 2018Article
- Thyroid Function and Thyroid Autoimmunity in Relation to Weight Status and Cardiovascular Risk Factors in Children and Adolescents: A Population-Based Study.Journal of clinical research in pediatric endocrinology · 2016Observational
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of the presented study was to evaluate the prevalence of isolated hyperthyrotropinemia (IH) in obese children and the relation between anthropometric and metabolic parameters.
methodsHospital records of the children, who presented to the Pediatric Endocrinology outpatient clinic of our institution with obesity, and age and gender-matched healthy children, who had undergone thyroid function test for any reason were retrospectively reviewed.
resultsThe prevalence of IH was significantly higher in the obese group than in the controls (9.2 and 3.8 %, respectively). Body mass index-standard deviation score (BMI-SDS), thyroid-stimulating hormone (TSH), lipid parameters were significantly different in the obese group than in the control group. A positive correlation between TSH and BMI-SDS and negative correlation between TSH and free T4 (fT4) levels were found in obese subjects. Stepwise multiple linear regression analysis confirmed that BMI-SDS, fT4 and triglyceride levels were the strongest independent variables correlated with TSH level in obese subjects (r (2) = 0.046, p = 0.001).
conclusionsIH prevalence is higher in obese children as compared to healthy children and the increase in TSH level correlates negatively with serum fT4 and positively with BMI-SDS and triglyceride levels in obese children.
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