ReviewDevelopmental medicine and child neurology2014
Meaningfulness of mean group results for determining the optimal motor rehabilitation program for an individual child with cerebral palsy.
Review in Developmental medicine and child neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effects of Dopamine on Motor Recovery and Training in Adults and Children With Nonprogressive Neurological Injuries: A Systematic Review.Neurorehabilitation and neural repair · 2019Pooled it
- Constraint-induced movement therapy in children with unilateral cerebral palsy.The Cochrane database of systematic reviews · 2019Pooled it
- Relationship between changes in motor capacity and objectively measured motor performance in ambulatory children with spastic cerebral palsy.Child: care, health and development · 2020Trial
- Genetic Variation in the Dopamine System Influences Intervention Outcome in Children with Cerebral Palsy.EBioMedicine · 2018Trial
- A lower-extremity exoskeleton improves knee extension in children with crouch gait from cerebral palsy.Science translational medicine · 2017Trial
- Study protocol for Full Speed Ahead: an intervention for improved activities in daily life through Frame Running and Goal directed training.BMC pediatrics · 2026Article
- Assessment of cortical activity, functional connectivity, and neuroplasticity in cerebral palsy using functional near-infrared spectroscopy: A scoping review.Developmental medicine and child neurology · 2025Article
- EFFECTS OF HIGHER- AND LOWER-INTENSITY EXERCISE ON FITNESS, COGNITION, MOTOR FUNCTION, AND QUALITY OF LIFE IN ADULTS WITH TRAUMATIC BRAIN INJURY.Journal of rehabilitation medicine. Clinical communications · 2025Article
- Article
- The Small Step Early Intervention Program for Infants at High Risk of Cerebral Palsy: A Single-Subject Research Design Study.Journal of clinical medicine · 2024Article
- Functional outcome after selective dorsal rhizotomy: a retrospective case control study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- Children With Bilateral Cerebral Palsy Exhibit Bimanual Asymmetric Motor Deficits and EEG Evidence of Dominant Sensorimotor Hemisphere Overreliance During Reaching.Neurorehabilitation and neural repair · 2023Article
- Detecting Movement Changes in Children with Hemiparesis after Upper Limb Therapies: A Responsiveness Analysis of a 3D Bimanual Protocol.Sensors (Basel, Switzerland) · 2023Article
- Comprehensive personalized ankle joint shape analysis of children with cerebral palsy from pediatric MRI.Frontiers in bioengineering and biotechnology · 2022Article
- Functional and Structural Brain Connectivity in Children With Bilateral Cerebral Palsy Compared to Age-Related Controls and in Response to Intensive Rapid-Reciprocal Leg Training.Frontiers in rehabilitation sciences · 2022Article
- Cortisol Levels in Infants with Central Coordination Disorders during Vojta Therapy.Children (Basel, Switzerland) · 2021Article
- Evaluating a Therapeutic Powered Mobility Camp for Children with Severe Cerebral Palsy.Canadian journal of occupational therapy. Revue canadienne d'ergotherapie · 2021Article
- Article
- Pilot Evaluation of a School-Based Programme Focused on Activity, Fitness, and Function among Children with Cerebral Palsy at GMFCS Level IV: Single-Subject Research Design.Physiotherapy Canada. Physiotherapie Canada · 2020Article
- Motor Learning Abilities Are Similar in Hemiplegic Cerebral Palsy Compared to Controls as Assessed by Adaptation to Unilateral Leg-Weighting during Gait: Part I.Frontiers in human neuroscience · 2017Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
As research on the efficacy or effectiveness of interventions to improve motor functioning in cerebral palsy (CP) has accumulated and been incorporated into systematic reviews, the foundation for evidence-based practice in CP is growing. To determine whether an intervention is effective, clinical trials report mean group differences. However, even if a statistically significant mean group effect is found, this does not imply that this intervention was effective for each study participant or ensure positive outcomes for all with CP. A personalized approach to medical care is currently being advocated based primarily on increasingly recognized genetic variations in individual responses to medications and other therapies. A similar approach is also warranted, and perhaps more justifiable, in CP which includes a heterogeneous group of disorders. Even interventions deemed highly effective in CP demonstrate a range of individual responses along a continuum from a negative or negligible response to a strong positive effect, the bases for which remain incompletely understood. This narrative review recommends that the next critical step in advancing evidence-based practice is to implement research strategies to identify patient factors that predict treatment responses so we can not only answer the question 'what works', but also 'what works best, for whom'.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.