Evidence map›Paper›PMID 24919805›Full record

ArticleLeukemia2014

Revisiting guidelines for integration of flow cytometry results in the WHO classification of myelodysplastic syndromes-proposal from the International/European LeukemiaNet Working Group for Flow Cytometry in MDS.

A Porwit, A A van de Loosdrecht, P Bettelheim, L Eidenschink Brodersen, K Burbury, E Cremers, M G Della Porta, R Ireland, U Johansson, S Matarraz and 11 more

Abstract read
PubMed Publisher
In one paragraph

Article in Leukemia, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it, 145 citations in OpenAlex.

  1. Guideline
  2. Review
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  11. Review
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  16. Article
  17. Article
  18. Computational flow cytometry as a diagnostic tool in suspected-myelodysplastic syndromes.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2021
    Article
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 15 institutions in 11 countries.

A PorwitDepartment of Pathobiology and Laboratory Medicine, University of Toronto, University Health Network, Toronto General Hospital, Toronto, Ontario, Canada.
A A van de LoosdrechtDepartment of Hematology, Cancer Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.
P BettelheimFirst Medical Department, Elisabethinen Hospital, Linz, Austria.
L Eidenschink BrodersenHematoLogics, Inc., Seattle, WA, USA.
K BurburyDivision of Cancer Medicine, Peter MacCallum Cancer Centre, East Melbourne, Melbourne, Victoria, Australia.
E CremersDepartment of Hematology, Cancer Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.
M G Della PortaDepartment of Hematology and Oncology, Fondazione IRCCS Policlinico San Matteo, Pavia, and University of Pavia, Pavia, Italy.
R IrelandKing's College Hospital, London, UK.
U JohanssonUniversity Hospitals, Bristol, UK.
S MatarrazServicio Central de Citometría, Centro de Investigación del Cáncer, Instituto de Biologia Celular y Molecular del Cáncer CSIC/USAL/IBSAL) and Department of Medicine, Universidad de Salamanca, Salamanca, Spain.
K OgataMetropolitan Research Center for Blood Disorders MRC JAPAN, Midorigaoka, Chofu, Tokyo, Japan.
A OrfaoServicio Central de Citometría, Centro de Investigación del Cáncer, Instituto de Biologia Celular y Molecular del Cáncer CSIC/USAL/IBSAL) and Department of Medicine, Universidad de Salamanca, Salamanca, Spain.
F PreijersDepartment of Hematology, St Radboud University Medical Center, Nijmegen, The Netherlands.
K PsarraDepartment of Immunology-Histocompatibility, Evangelismos Hospital, Athens, Greece.
D SubiráDepartment of Hematology, Hospital Universitario de Guadalajara, Guadalajara, Spain.
P ValentDepartment of Internal Medicine I, Division of Hematology and Hemostaseology and Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Vienna, Austria.
V H J van der VeldenDepartment of Immunology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
D WellsHematoLogics, Inc., Seattle, WA, USA.
T M WestersDepartment of Hematology, Cancer Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.
W KernMLL Munich Leukemia Laboratory, Munich, Germany.
M C BénéService d'Hématologie Biologique, CHU de Nantes, Nantes, France.
Amsterdam UMC Location Vrije Universiteit Amsterdam · NLCentro de Investigación del Cáncer · ESCentre Hospitalier Universitaire de Nantes · FRErasmus MC · NLEvangelismos Hospital · GRHospital Universitario de Guadalajara · ESKing's College Hospital · GBKrankenhaus der Elisabethinen · ATLudwig Boltzmann Institute for Cardiovascular Research · ATMidorigaoka Hospital · JPMunich Leukemia Laboratory (Germany) · DEPeter MacCallum Cancer Centre · AURadboud University Nijmegen · NLUniversity Health Network · CAUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Definite progress has been made in the exploration of myelodysplastic syndromes (MDS) by flow cytometry (FCM) since the publication of the World Health Organization 2008 classification of myeloid neoplasms. An international working party initiated within the European LeukemiaNet and extended to include members from Australia, Canada, Japan, Taiwan and the United States has, through several workshops, developed and subsequently published consensus recommendations. The latter deal with preanalytical precautions, and propose small and large panels, which allow evaluating immunophenotypic anomalies and calculating myelodysplasia scores. The current paper provides guidelines that strongly recommend the integration of FCM data with other diagnostic tools in the diagnostic work-up of MDS.

Indexed as

EuropeFlow CytometryGuidelines as TopicHumansMyelodysplastic SyndromesWorld Health Organization

Identifiers

PMID24919805
OpenAlexW2013169247

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.