ArticlePloS one2014
Adaptive evolution of mitochondrial energy metabolism genes associated with increased energy demand in flying insects.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 76 citations in OpenAlex.
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- Genetics of flight in spongy moths (Lymantria dispar ssp.): functionally integrated profiling of a complex invasive trait.BMC genomics · 2024Article
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- Comparative mitogenomic analysis of subterranean and surface amphipods (Crustacea, Amphipoda) with special reference to the family Crangonyctidae.BMC genomics · 2024Article
- Mitochondrial genomes of soft scales (Hemiptera: Coccidae): features, structures and significance.BMC genomics · 2023Article
- Adaptive evidence of mitochondrial genes in Pteromalidae and Eulophidae (Hymenoptera: Chalcidoidea).PloS one · 2023Article
- The First Complete Mitochondrial Genome ofGenes · 2022Article
- Genetic Drift and Purifying Selection Shaped Mitochondrial Genome Variation in the High Royal Jelly-Producing Honeybee Strain (Frontiers in genetics · 2022Article
- Complete mitochondrial genomes reveal robust phylogenetic signals and evidence of positive selection in horseshoe bats.BMC ecology and evolution · 2021Article
- Comparative Mitogenomes of TwoInsects · 2021Article
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- The complete mitogenome ofEcology and evolution · 2021Article
- Mechanical Permeabilization as a New Method for Assessment of Mitochondrial Function in Insect Tissues.Methods in molecular biology (Clifton, N.J.) · 2021Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Insects are unique among invertebrates for their ability to fly, which raises intriguing questions about how energy metabolism in insects evolved and changed along with flight. Although physiological studies indicated that energy consumption differs between flying and non-flying insects, the evolution of molecular energy metabolism mechanisms in insects remains largely unexplored. Considering that about 95% of adenosine triphosphate (ATP) is supplied by mitochondria via oxidative phosphorylation, we examined 13 mitochondrial protein-encoding genes to test whether adaptive evolution of energy metabolism-related genes occurred in insects. The analyses demonstrated that mitochondrial DNA protein-encoding genes are subject to positive selection from the last common ancestor of Pterygota, which evolved primitive flight ability. Positive selection was also found in insects with flight ability, whereas no significant sign of selection was found in flightless insects where the wings had degenerated. In addition, significant positive selection was also identified in the last common ancestor of Neoptera, which changed its flight mode from direct to indirect. Interestingly, detection of more positively selected genes in indirect flight rather than direct flight insects suggested a stronger selective pressure in insects having higher energy consumption. In conclusion, mitochondrial protein-encoding genes involved in energy metabolism were targets of adaptive evolution in response to increased energy demands that arose during the evolution of flight ability in insects.
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