ArticleInflammatory bowel diseases2014
Impact of mode of delivery on outcomes in patients with perianal Crohn's disease.
Article in Inflammatory bowel diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 46 citations in OpenAlex.
- Effects of 12-Week Resistance Training on Metabolic and Immune Responses in Normal-Weight and Older Women with Obesity.International journal of molecular sciences · 2026Article
- Understanding Inflammatory Bowel Disease in Women From Puberty to Menopause.Gastroenterology & hepatology · 2025Article
- Enhancing Crohn's disease management during pregnancy: innovations in therapeutic approaches and cutting-edge monitoring practices.BMC pregnancy and childbirth · 2025Observational
- Pregnancy in Patients with Inflammatory Bowel Disease: A Narrative Review.Visceral medicine · 2025Review
- Navigating Reproductive Care in Patients With Inflammatory Bowel Disease: A Comprehensive Review.Journal of Crohn's & colitis · 2024Review
- The mode of delivery does not influence the occurrence of post-partum perianal disease flares in patients with inflammatory bowel disease.BMC gastroenterology · 2024Article
- Pregnancy in Patients with Inflammatory Bowel Diseases-A Literature Review.Life (Basel, Switzerland) · 2023Review
- Effects of Different Delivery Modes on Pelvic Floor Function in Parturients 6-8 Weeks after Delivery Using Transperineal Four-Dimensional Ultrasound.Disease markers · 2022Article
- Review of pregnancy in Crohn's disease and ulcerative colitis.Therapeutic advances in gastroenterology · 2021Review
- Incidence and Predictors of Flares in the Postpartum Year Among Women With Inflammatory Bowel Disease.Inflammatory bowel diseases · 2020Article
- Predictors of Cesarean Delivery in Pregnant Women with Inflammatory Bowel Disease.Journal of the Canadian Association of Gastroenterology · 2018Article
- Indications for Mode of Delivery in Pregnant Women with Inflammatory Bowel Disease.Inflammatory bowel diseases · 2017Article
- First-in-Human Case Study: Pregnancy in Women With Crohn's Perianal Fistula Treated With Adipose-Derived Stem Cells: A Safety Study.Stem cells translational medicine · 2015Article
- Mode of childbirth and long-term outcomes in women with inflammatory bowel diseases.Digestive diseases and sciences · 2015Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundCrohn's disease (CD) often affects women during the reproductive years. Although several studies have examined the impact of pregnancy on luminal disease, limited literature exists in those with perianal CD. Decision regarding mode of delivery is a unique challenge in such patients due to concerns regarding the effect of pelvic floor trauma during delivery on preexisting perianal involvement.
methodsWe performed a retrospective chart review of patients with CD with established perianal disease undergoing either vaginal delivery or caesarean section (C-section) at our institutions. We examined the occurrence of symptomatic perianal disease flares within 5 years after delivery in such women compared with nonpregnant CD controls. We also compared the occurrence of such flares between the 2 modes of delivery in women with established perianal CD.
resultsWe identified 61 pregnant patients with CD with established perianal disease (11 vaginal delivery, 50 through C-section) and 61 nonpregnant CD controls with perianal disease. One-third of the C-sections were primarily for obstetric indications. Six of the vaginal deliveries were complicated. Approximately, 36% of cases had a symptomatic perianal flare within 1 year after delivery. This was similar across both modes of delivery (P = 0.53) and similar to nonpregnant patients with CD. There was no difference in the rates of perianal surgical intervention or luminal disease flares in our population based on mode of delivery or between pregnant patients with CD and nonpregnant CD controls.
conclusionsWe observed no difference in risk of symptomatic perianal flares in patients with established perianal CD delivering vaginally or through C-section.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.