ArticleUnited European gastroenterology journal2013
Pharyngeal pH alone is not reliable for the detection of pharyngeal reflux events: A study with oesophageal and pharyngeal pH-impedance monitoring.
Article in United European gastroenterology journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Guideline
- Salivary pH testing in Laryngopharyngeal Reflux Disease.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Diagnosis of Laryngopharyngeal Reflux: Past, Present, and Future-A Mini-Review.Diagnostics (Basel, Switzerland) · 2023Review
- Validation of Pharyngeal Acid Reflux Episodes Using Hypopharyngeal Multichannel Intraluminal Impedance-pH.Journal of neurogastroenterology and motility · 2023Article
- Clinical Update Findings about pH-Impedance Monitoring Features in Laryngopharyngeal Reflux Patients.Journal of clinical medicine · 2022Review
- How I Approach Laryngopharyngoesophageal Reflux (LPR).Current gastroenterology reports · 2021Review
- Review
- Evaluation of Oropharyngeal pH-Monitoring in the Assessment of Laryngopharyngeal Reflux.Journal of clinical medicine · 2021Article
- Simultaneous Evaluation of Laryngopharyngeal Reflux and Swallowing Function Using Hypopharyngeal Multichannel Intraluminal Impedance Measurements in Neurologically Impaired Patients.Journal of neurogastroenterology and motility · 2021Article
- Pepsin and oropharyngeal pH monitoring to diagnose patients with laryngopharyngeal reflux.The Laryngoscope · 2020Article
- Acidic Pharyngeal Reflux Does Not Correlate with Symptoms and Laryngeal Injury Attributed to Laryngopharyngeal Reflux.Digestive diseases and sciences · 2019Article
- Hypopharyngeal multichannel intraluminal impedance leads to the promising outcome of antireflux surgery in Japanese population with laryngopharyngeal reflux symptoms.Surgical endoscopy · 2018Article
- Pharyngeal pH monitoring in gastrectomy patients - what do we really measure?United European gastroenterology journal · 2016Article
- Dental erosions and other extra-oesophageal symptoms of gastro-oesophageal reflux disease: Evidence, treatment response and areas of uncertainty.United European gastroenterology journal · 2015Article
- Laryngopharyngeal Reflux: Historical Perspectives, Current Diagnostics and Therapies, and Remaining Challenges.Acta gastroenterologica LatinoamericanaReview
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8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundPharyngeal pH probes and pH-impedance catheters have been developed for the diagnosis of laryngo-pharyngeal reflux.
objectiveTo determine the reliability of pharyngeal pH alone for the detection of pharyngeal reflux events.
methods24-h pH-impedance recordings performed in 45 healthy subjects with a bifurcated probe for detection of pharyngeal and oesophageal reflux events were reviewed. Pharyngeal pH drops to below 4 and 5 were analysed for the simultaneous occurrence of pharyngeal reflux, gastro-oesophageal reflux, and swallows, according to impedance patterns.
resultsOnly 7.0% of pharyngeal pH drops to below 5 identified with impedance corresponded to pharyngeal reflux, while 92.6% were related to swallows and 10.2 and 13.3% were associated with proximal and distal gastro-oesophageal reflux events, respectively. Of pharyngeal pH drops to below 4, 13.2% were related to pharyngeal reflux, 87.5% were related to swallows, and 18.1 and 21.5% were associated with proximal and distal gastro-oesophageal reflux events, respectively.
conclusionsThis study demonstrates that pharyngeal pH alone is not reliable for the detection of pharyngeal reflux and that adding distal oesophageal pH analysis is not helpful. The only reliable analysis should take into account impedance patterns demonstrating the presence of pharyngeal reflux event preceded by a distal and proximal reflux event within the oesophagus.
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