Evidence map›Paper›PMID 24917987›Full record

ArticleUnited European gastroenterology journal2013

A survey of pharmacological and nonpharmacological treatment of functional gastrointestinal disorders.

Edith Lahner, Stefano Bellentani, Rudy De Bastiani, Cesare Tosetti, Michele Cicala, Gianluca Esposito, Paolo Arullani, Bruno Annibale

Open access · bronzeAbstract read
In one paragraph

Article in United European gastroenterology journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 4 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 4 syntheses or guidelines pooled it, 86 citations in OpenAlex.

  1. Pooled it
  2. Potential Benefit With Complementary and Alternative Medicine in Irritable Bowel Syndrome: A Systematic Review and Meta-analysis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2021
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  7. Pharmaceutical biology · 2025
    Article
  8. [Irritable Bowel Syndrome].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025
    Review
  9. Endometriosis and Nutrition: Therapeutic Perspectives.Journal of clinical medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Edith LahnerUniversity 'Sapienza', Rome, Italy.
Stefano BellentaniStudy Group 'Primary Care in Gastroenterology', Italian Society of Gastroenterology, Rome, Italy.
Rudy De BastianiStudy Group 'Primary Care in Gastroenterology', Italian Society of Gastroenterology, Rome, Italy.
Cesare TosettiStudy Group 'Primary Care in Gastroenterology', Italian Society of Gastroenterology, Rome, Italy.
Michele CicalaUniversity Campus Bio Medico, Rome, Italy.
Gianluca EspositoUniversity 'Sapienza', Rome, Italy.
Paolo ArullaniItalian Foundation 'Aldo Torsoli' for Digestive, Liver and Pancreatic Diseases, Rome, Italy.
Bruno AnnibaleUniversity 'Sapienza', Rome, Italy.
Italian Society of Physiotherapy · ITSapienza University of Rome · ITFondazione Italiana Fegato · ITUniversità Campus Bio-Medico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTreatment of functional gastrointestinal disorders (FGIDs) is based on symptoms relieve by conventional drugs, but increasingly complementary and alternative medicine (CAM) is used.

objectiveThis survey aimed to investigate the current treatments used by FGIDs patients.

methodsA total of 25 Italian gastroenterologists interviewed outpatients on gastrointestinal symptoms and treatments (pharmacological, CAM, diet/dietary supplements) used during the last year to relieve FGIDs. Consecutive adults with FGIDs according to Rome III were included.

resultsOf the 199 patients, 81% used conventional drugs, 64.3% diet/dietary supplements, and 48.7% CAM. Conventional drugs, diet/dietary supplements, or CAM as exclusive treatment were used by 24.6, 6, and 2.5% of patients, respectively. Two-thirds used more than one treatment: 34.7% conventional drugs, CAM, and diet/dietary supplements, 17.1% conventional drugs and diet/dietary supplements, 10.1% diet and CAM, and 5% conventional drugs and CAM. Benefits and adverse effects were similar for conventional drugs and nonpharmacological treatments. Males (OR 2.4) without lower GI symptoms (OR 5.4) used more frequently exclusive pharmacological treatment of FGIDs.

conclusionsConventional drugs are the preferred treatment for FGID. CAM and dietary modifications are more likely used as an adjunct to rather than instead of conventional drugs. Adverse effects occurred in all treatments.

Indexed as

Complementary and alternative medicinefunctional dyspepsiafunctional gastrointestinal disordersirritable bowel syndrometreatment

Identifiers

PMID24917987
PMCPMC4040767
OpenAlexW2101795938

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.