ArticleFrontiers in computational neuroscience2014
Population coding in mouse visual cortex: response reliability and dissociability of stimulus tuning and noise correlation.
Article in Frontiers in computational neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed.
- Convergent multidimensional neural phenotypes in human patients and schizophrenia-relevant mouse models identify reduced recurrent excitation in cortical circuits.medRxiv : the preprint server for health sciences · 2026Article
- Nonuniform spike count shared variability in the mouse early visual system.Journal of neurophysiology · 2026Article
- Article
- Interdigitating Modules for Visual Processing During Locomotion and Rest in Mouse V1.bioRxiv : the preprint server for biology · 2025Article
- Network influence determines the impact of cortical ensembles on stimulus detection.bioRxiv : the preprint server for biology · 2024Article
- Article
- Neurogliaform Cells Exhibit Laminar-specific Responses in the Visual Cortex and Modulate Behavioral State-dependent Cortical Activity.Research square · 2024Article
- Neurogliaform Cells Exhibit Laminar-specific Responses in the Visual Cortex and Modulate Behavioral State-dependent Cortical Activity.bioRxiv : the preprint server for biology · 2024Article
- Multicore fiber optic imaging reveals that astrocyte calcium activity in the mouse cerebral cortex is modulated by internal motivational state.Nature communications · 2024Article
- Comparison of orientation encoding across layers within single columns of primate V1 revealed by high-density recordings.Frontiers in neural circuits · 2024Article
- An adaptive behavioral control motif mediated by cortical axo-axonic inhibition.Nature neuroscience · 2023Article
- Sound Improves Neuronal Encoding of Visual Stimuli in Mouse Primary Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- An adaptive behavioral control motif mediated by cortical axo-axonic inhibition.bioRxiv : the preprint server for biology · 2023Article
- A data-based large-scale model for primary visual cortex enables brain-like robust and versatile visual processing.Science advances · 2022Article
- Increased Reliability of Visually-Evoked Activity in Area V1 of the MECP2-Duplication Mouse Model of Autism.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Development of visual response selectivity in cortical GABAergic interneurons.Nature communications · 2022Article
- Article
- Article
- Disparity Sensitivity and Binocular Integration in Mouse Visual Cortex Areas.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The primary visual cortex is an excellent model system for investigating how neuronal populations encode information, because of well-documented relationships between stimulus characteristics and neuronal activation patterns. We used two-photon calcium imaging data to relate the performance of different methods for studying population coding (population vectors, template matching, and Bayesian decoding algorithms) to their underlying assumptions. We show that the variability of neuronal responses may hamper the decoding of population activity, and that a normalization to correct for this variability may be of critical importance for correct decoding of population activity. Second, by comparing noise correlations and stimulus tuning we find that these properties have dissociated anatomical correlates, even though noise correlations have been previously hypothesized to reflect common synaptic input. We hypothesize that noise correlations arise from large non-specific increases in spiking activity acting on many weak synapses simultaneously, while neuronal stimulus response properties are dependent on more reliable connections. Finally, this paper provides practical guidelines for further research on population coding and shows that population coding cannot be approximated by a simple summation of inputs, but is heavily influenced by factors such as input reliability and noise correlation structure.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.