Evidence map›Paper›PMID 24917685›Full record

ArticleBiology of sport2014

Is gnb3 c825t polymorphism associated with elite status of polish athletes?

M Sawczuk, A Maciejewska-Karłowska, P Cięszczyk, A Leońska-Duniec

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology of sport, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Genes · 2019
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

M SawczukFaculty of Physical Education and Health Promotion, University of Szczecin, Szczecin, Poland.
A Maciejewska-KarłowskaFaculty of Physical Education and Health Promotion, University of Szczecin, Szczecin, Poland.
P CięszczykFaculty of Physical Education and Health Promotion, University of Szczecin, Szczecin, Poland ; Department of Sport Education, Academy of Physical Education and Sport, Gdańsk, Poland.
A Leońska-DuniecFaculty of Physical Education and Health Promotion, University of Szczecin, Szczecin, Poland ; Department of Sport Education, Academy of Physical Education and Sport, Gdańsk, Poland.
University of Szczecin · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledThe GNB3 gene encodes the beta 3 subunit of heterotrimeric G-proteins that are key components of intracellular signal transduction between G protein-coupled receptors (GPCR) and intracellular effectors and might be considered as a potential candidate gene for physical performance.

objectivesThe aim of this study was to compare frequency distribution of the common C to T polymorphism at position 825 (C825T) of the GNB3 gene between athletes and nonathletic controls of the Polish population as well as to compare the genotype distribution and allele frequency of C825T variants within a group of athletes, i.e. between athletes of sports of different metabolic demands and competitive levels.

methodsThe study was performed in a group of 223 Polish athletes of the highest nationally competitive standard (123 endurance-oriented athletes and 100 strength/ power athletes). Control samples were prepared from 354 unrelated, sedentary volunteers.

resultsThe χ(2) test revealed no statistical differences between the endurance-oriented athletes and the control group or between sprint/strength athletes and the control group across the GNB3 825C/T genotypes. There were no male-female genotype or allele frequency differences in controls or in either strength/power or endurance-oriented athletes. No statistically significant differences in either allele frequencies or genotype distribution were noted between the top-elite, elite or sub-elite of endurance-oriented and strength/power athletes and the control group.

conclusionsNo association between elite status of Polish athletes and the GNB3 C825T polymorphic site has been found.

Indexed as

elite athletes statusgene polymorphismGNB3 C825Tperformance

Identifiers

PMID24917685
PMCPMC3994581
OpenAlexW2153123223

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.