ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2014
Cranial metastatic alveolar rhabdomyosarcoma mimicking hematological malignancy in an adolescent boy.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 5 citations in OpenAlex.
- Spontaneous tumor lysis syndrome in an adult with alveolar rhabdomyosarcoma: a challenging diagnosis.Oxford medical case reports · 2024Article
- Alveolar rhabdomyosarcoma metastatic to the brain.BMJ case reports · 2021Article
- Vacuolated Blasts in the Bone Marrow of a Child with RhabdomyosarcomaTurkish journal of haematology : official journal of Turkish Society of Haematology · 2020Article
- Rhabdomyosarcoma debut masquerading as acute lymphoblastic leukemia: A case report and review of the literature.Clinical case reports · 2019Article
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8 authors at 2 institutions in 1 country.
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Abstract
backgroundWidespread alveolar rhabdomyosarcoma (ARMS) with bone marrow involvement and with an unknown primary tumor, especially presenting with acute tumor lysis syndrome can be easily misdiagnosed as a hematological malignancy. Furthermore, brain metastasis of ARMS is rare seen in children. CASE REPORT: Herein, we report a 14-year-old boy presenting with acute tumor lysis syndrome due to bone marrow invasion of ARMS, who was diagnosed after abdominal paraaortic lymph node biopsy. Despite radiological and nuclear medicine imaging, the primary tumor site could not be found. He was treated with vincristine, topotecan, and cyclophosphamide for 42 weeks. Six months after the completion of treatment, he suffered from severe headache, blurred vision, right hemiplegia, and severe bone pain. Cranial magnetic resonance imaging showed multiple hemorrhagic infarctions. Brain biopsy showed brain metastasis with PAX3-FKHR fusion transcript.
conclusionThe clinicians must be vigilant about solely brain metastasis in ARMS without additional metastasis.
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