ArticleBMC cancer2014
Attributable fraction of alcohol consumption on cancer using population-based nationwide cancer incidence and mortality data in the Republic of Korea.
Article in BMC cancer, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Preventable Cancers Caused by Infection in Korea From 2015 to 2030.Journal of Korean medical science · 2025Pooled it
- Population Attributable Fraction of Established Modifiable Risk Factors on Colorectal Cancer in Korea.Cancer research and treatment · 2021Pooled it
- Population attributable risks of modifiable reproductive factors for breast and ovarian cancers in Korea.BMC cancer · 2016Pooled it
- Association of Daily Alcohol Consumption and Drinking Patterns with Risk of Primary Malignant Brain Tumor in Korean Adults: A Retrospective Cohort Study.Journal of cancer prevention · 2026Article
- Fraction of cancer incidence and mortality attributable to dietary factors in Korea from 2015 to 2030.Epidemiology and health · 2025Article
- Alcohol and Periodontal Disease: A Narrative Review.Cureus · 2024Review
- Adherence to Cancer Prevention Guidelines and Cancer Incidence and Mortality: A Population-Based Cohort Study.Cancer research and treatment · 2023Article
- Cancer incidence among male construction workers in Korea: a standardized incidence ratio analysis, 2009-2015.Epidemiology and health · 2023Article
- Modifiable lifestyle factors have a larger contribution to colorectal neoplasms than family history.BMC cancer · 2022Article
- Burden of cancer attributable to modifiable factors in Japan in 2015.Global health & medicine · 2022Article
- Population attributable fractions of modifiable cancer risk factors in Korea: a systematic review protocol.BMJ open · 2022Article
- Epidemiology, Risk Factors, and Prevention of Colorectal Cancer-An English Version.Journal of the anus, rectum and colon · 2022Review
- Heterogenous Effect of Risk Factors on Breast Cancer across the Breast Density Categories in a Korean Screening Population.Cancers · 2020Article
- Role of aldehyde dehydrogenases, alcohol dehydrogenase 1B genotype, alcohol consumption, and their combination in breast cancer in East-Asian women.Scientific reports · 2020Article
- Risk of colorectal cancer in patients with alcoholism: A nationwide, population-based nested case-control study.PloS one · 2020Article
- Geographical Variations and Trends in Major Cancer Incidences throughout Korea during 1999-2013.Cancer research and treatment · 2018Article
- Estimating the Burden of Cancer and Treatment Cost Related to Alcohol Consumption in Indonesia: a Descriptive StudyAsian Pacific journal of cancer prevention : APJCP · 2018Article
- Molecular Basis of Alcohol-Related Gastric and Colon Cancer.International journal of molecular sciences · 2017Review
- Cancers Attributable to Alcohol Consumption in Nigeria: 2012-2014.Frontiers in oncology · 2017Article
- Interaction between MLL3 genetic polymorphisms, smoking, and alcohol drinking in laryngeal cancer: a case-control study.Cancer medicine · 2016Article
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Authors and funding
12 authors at 7 institutions in 6 countries.
Funding
Abstract
backgroundIn the Republic of Korea, cancer is the most common cause of death, and cancer incidence and mortality rates are the highest in East Asia. As alcoholic beverages are carcinogenic to humans, we estimated the burden of cancer related to alcohol consumption in the Korean population.
methodsThe cancer sites studied were those for which there is convincing evidence of a positive association with alcohol consumption: oral cavity, pharynx, esophagus, colon, rectum, liver, larynx and female breast. Sex- and cancer-specific population attributable fractions (PAF) were calculated based on: 1) the prevalence of alcohol drinkers among adults ≥ 20 years of age in 1989; 2) the average daily alcohol consumption (g/day) among drinkers in 1998; 3) relative risk (RR) estimates for the association between alcohol consumption and site-specific cancer incidence obtained either from a large Korean cohort study or, when more than one Korean study was available for a specific cancer site, meta-analyses were performed and the resulting meta-RRs were used; 4) national cancer incidence and mortality data from 2009.
resultsAmong men, 3% (2,866 cases) of incident cancer cases and 2.8% (1,234 deaths) of cancer deaths were attributable to alcohol consumption. Among women, 0.5% (464 cancer cases) of incident cancers and 0.1% (32 deaths) of cancer deaths were attributable to alcohol consumption. In particular, the PAF for alcohol consumption in relation to oral cavity cancer incidence among Korean men was 29.3%, and the PAFs for pharyngeal and laryngeal cancer incidence were 43.3% and 25.8%, respectively. Among Korean women, the PAF for colorectal cancer incidence was the highest (4.2%) and that for breast cancer incidence was only 0.2%. Avoiding alcohol consumption, or reducing it from the median of the highest 4th quartile of consumption (56.0 g/day for men, 28.0 g/day for women) to the median of the lowest quartile (2.80 g/day for men, 0.80 g/day for women), would reduce the burden of alcohol-related cancers in Korea.
conclusionsA reduction in alcohol consumption would decrease the cancer burden and a significant impact is anticipated specifically for the cancers oral cavity, pharynx, and larynx among men in the Republic of Korea.
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