Evidence map›Paper›PMID 24917130›Full record

ArticleGenome biology2014

Mapping-by-sequencing accelerates forward genetics in barley.

Martin Mascher, Matthias Jost, Joel-Elias Kuon, Axel Himmelbach, Axel Aßfalg, Sebastian Beier, Uwe Scholz, Andreas Graner, Nils Stein

Abstract read
In one paragraph

Article in Genome biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed.

  1. Article
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  6. Review
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  10. Characterization of a barley (Frontiers in plant science · 2023
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. The barley mutant multiflorus2.b reveals quantitative genetic variation for new spikelet architecture.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022
    Article
  17. Review
  18. Article
  19. Genomics and breeding innovations for enhancing genetic gain for climate resilience and nutrition traits.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021
    Review
  20. Article

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Martin Mascher
Matthias Jost
Joel-Elias Kuon
Axel Himmelbach
Axel Aßfalg
Sebastian Beier
Uwe Scholz
Andreas Graner
Nils Stein

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mapping-by-sequencing has emerged as a powerful technique for genetic mapping in several plant and animal species. As this resequencing-based method requires a reference genome, its application to complex plant genomes with incomplete and fragmented sequence resources remains challenging. We perform exome sequencing of phenotypic bulks of a mapping population of barley segregating for a mutant phenotype that increases the rate of leaf initiation. Read depth analysis identifies a candidate gene, which is confirmed by the analysis of independent mutant alleles. Our method illustrates how the genomic resources of barley together with exome resequencing can underpin mapping-by-sequencing.

Indexed as

Chromosome MappingCytochrome P-450 Enzyme SystemGene FrequencyGenes, PlantGenetic Association StudiesGenetic LociHordeumMutagenesisPhenotypePhylogenyPlant ProteinsSequence Analysis, DNACytochrome P-450 Enzyme SystemPlant Proteins

Identifiers

PMID24917130
PMCPMC4073093

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.